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CAS

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66422-03-5

9-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}-3-oxa-9-aza-6-azoniaspiro[5.5]undecane is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 66422-03-5 Structure

  • Basic information

    1. Product Name: 9-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}-3-oxa-9-aza-6-azoniaspiro[5.5]undecane
    2. Synonyms:
    3. CAS NO:66422-03-5
    4. Molecular Formula: C24H29F3N3OS
    5. Molecular Weight: 464.5662
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 66422-03-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 9-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}-3-oxa-9-aza-6-azoniaspiro[5.5]undecane(CAS DataBase Reference)
    10. NIST Chemistry Reference: 9-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}-3-oxa-9-aza-6-azoniaspiro[5.5]undecane(66422-03-5)
    11. EPA Substance Registry System: 9-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}-3-oxa-9-aza-6-azoniaspiro[5.5]undecane(66422-03-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 66422-03-5(Hazardous Substances Data)

66422-03-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 66422-03-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,4,2 and 2 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 66422-03:
(7*6)+(6*6)+(5*4)+(4*2)+(3*2)+(2*0)+(1*3)=115
115 % 10 = 5
So 66422-03-5 is a valid CAS Registry Number.

66422-03-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 9-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-3-oxa-9-aza-6-azoniaspiro[5.5]undecane,chloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66422-03-5 SDS

66422-03-5Downstream Products

66422-03-5Relevant articles and documents

Potential CNS antitumor agents - Phenothiazines. II: Fluphenazine analogs

Hirata,Peng,Driscoll

, p. 157 - 162 (1978)

Fluphenazine was found to possess moderate, reproducible activity against the intraperitoneal L-1210 and P-388 leukemia murine tumor models. Seven ether derivatives of fluphenazine and eight compounds in which the terminal side-chain hydroxyl group was replaced by an amine function were prepared and evaluated in the intraperitoneal L-1210, P-388, and B16 melanoma systems as well as the intracerebral L-1210 and ependymoblastoma brain tumor models. While no substantial intracerebral activity was observed, seven derivatives possessed reproducible activity in the intraperitoneal L-1210 or P-388 system. Several gave T/C [(treated survival/control survival) x 100%] values of 150%. No B16 melanoma activity was observed. These compounds were also tested for their cytototoxic properties in culture against L-1210, P-388, and KB cells. The amine isosteres, while possessing little in vivo activity, were the most cytotoxic of the compounds prepared, with several having ED50 values 1 μg/ml.

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