66423-13-0Relevant academic research and scientific papers
Industrial production improvement process for (R)-2-(4-chlorine-2-methyl phenoxy) octyl propionate root retarder
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, (2018/11/22)
The invention discloses an industrial production improvement process for a (R)-2-(4-chlorine-2-methyl phenoxy) octyl propionate root retarder which can be used as a root retarder. The production process is characterized by comprising the following steps: by taking methylbenzene as a solvent, triethylamine as an acid-binding agent, and pyridine as a catalyst, carrying out sulfonation on L-ethyl lactate and paratoluensulfonyl chloride so as to obtain a corresponding sulfonyl ester intermediate product; under the promotion of sodium hydroxide, carrying out etherification on the sulfonyl ester intermediate product with 4-chlorine o-cresol so as to obtain an aromatic ester ether compound; at a certain temperature and pressure, carrying out ester exchange on the ester ether compound with n-octylalcohol, thereby obtaining the (R)-2-(4-chlorine-2-methyl phenoxy) octyl propionate. The (R)-2-(4-chlorine-2-methyl phenoxy) octyl propionate prepared by using the production improvement process disclosed by the invention is high in optical content, small in raw material optical loss and high in yield, and can be directly applied to process production of root puncturing resistant waterproof rolls. The production process has large application prospects.
Preparation method of octyl (R)-2-(4-chloro-2-methylphenoxy) propionate root retarder
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, (2018/04/01)
The invention discloses a preparation method of octyl (R)-2-(4-chloro-2-methylphenoxy) propionate which can be used as a root retarder. The preparation method comprises the following steps: with ethyl L-lactate as a raw material, sulfonating together with p-toluenesulfonyl chloride to obtain a corresponding sulfonyl ester compound; etherifying the sulfonyl ester compound and 4-chloro-o-cresol to obtain a corresponding aromatic ether ester compound; and finally, performing transesterification on the ether ester compound and n-octyl alcohol to obtain octyl (R)-2-(4-chloro-2-methylphenoxy) propionate. Octyl (R)-2-(4-chloro-2-methylphenoxy) propionate prepared by the preparation method provided by the invention is high in optical content, relatively small in optical loss of raw materials and relatively high in yield. The invention establishes a reaction system with the characteristics of simple preparation process, mild reaction condition and low cost, so that the problems that the compound is imported and has a scarce source are solved to a certain extent.
