66427-92-7

Upstream product

• 904791-68-0 (R)-phenyl-[O²,O³,O⁴-triacetyl-O⁶-(tetra-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranosyloxy]-acetic acid 
• 61091-11-0 Acetic acid (2R,3R,4S,5R,6R)-4,5-diacetoxy-2-((S)-cyano-phenyl-methoxy)-6-((2R,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-3-yl ester 
• 909100-37-4 O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl(1->6)-2,3,4-tri-O-acetyl-β-D-glucopyranosyl)trichloroacetimidate 
• 611-71-2 (R)-Mandelic Acid 
• 18423-99-9 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl (1->6)-2,3,4-tri-O-acetyl-β-D-glucopyranoside 

Relevant academic research and scientific papers

USE OF AMYGDALIN ANALOGUES FOR THE TREATMENT OF PSORIASIS

The compounds of formula (I), wherein n is an integer from 0 to 4; R1 is a radical selected from the group consisting of H, CH3, CH2-CH3, C(CH3)3, COOH, CONH2 and C≡CH; R2, R3, R4 and R5 ar

Synthesis and evaluation of diverse analogs of amygdalin as potential peptidomimetics of peptide T

Peptide T (ASTTTNYT) is a promising molecule to prevent the neuropsychometric symptoms of patients suffering AIDS and for the treatment of psoriasis. In order to fully prove its therapeutic benefits, efforts were put forward to design peptidomimetics of the peptide. In this direction, in a recent computational study the natural product amygdalin was identified as a prospective peptidomimetic of the peptide and later proved to exhibit a similar chemotactic profile to the peptide. However, the cyanide moiety of amygdalin provides to the molecule a toxic profile. The present study reports the synthesis of a set of amygdalin analogs lacking the cyanide group with improved chemotactic profiles.