664317-83-3 Usage
Chemical class
Indole derivative
Structural feature
A substituent methyl group attached to the phenyl ring
Pharmacological properties
Potential as a ligand for various biological receptors
Potential applications
Antipsychotic and analgesic agent, modulation of the endocannabinoid system
Relevance
Interest in medicinal chemistry and drug development
Research focus
Further investigation of its chemical properties and biological activities
Check Digit Verification of cas no
The CAS Registry Mumber 664317-83-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,4,3,1 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 664317-83:
(8*6)+(7*6)+(6*4)+(5*3)+(4*1)+(3*7)+(2*8)+(1*3)=173
173 % 10 = 3
So 664317-83-3 is a valid CAS Registry Number.
664317-83-3Relevant academic research and scientific papers
Analogues and derivatives of oncrasin-1, a novel inhibitor of the C-terminal domain of RNA polymerase II and their antitumor activities
Wu, Shuhong,Wang, Li,Guo, Wei,Liu, Xiaoying,Liu, Jinsong,Wei, Xiaoli,Fang, Bingliang
experimental part, p. 2668 - 2679 (2011/06/27)
To optimize the antitumor activity of oncrasin-1, a small molecule RNA polymerase II inhibitor, we evaluated 69 oncrasin-1 analogues for their cytotoxic activity against normal human epithelial cells and K-Ras mutant tumor cells. About 40 of those compoun
