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CAS

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664338-39-0

Arterolane, also known as OZ277 or RBx11160, is a synthetic trioxolane, a class of antimalarial drugs, specifically designed to be effective against drug-resistant malaria. It is characterized by a simpler chemical structure compared to other antimalarial drugs and is used in combination with piperaquine to treat uncomplicated Plasmodium falciparum malaria. Arterolane functions by rapidly and potently reducing parasitemia, which is the concentration of parasites in the blood, thereby alleviating symptoms and preventing disease progression. It is generally well-tolerated with minimal side effects.

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  • 664338-39-0 Structure

  • Basic information

    1. Product Name: Arterolane
    2. Synonyms: Arterolane;OZ 277
    3. CAS NO:664338-39-0
    4. Molecular Formula: C22H36N2O4
    5. Molecular Weight: 392.53224
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 664338-39-0.mol

  • Chemical Properties

    1. Melting Point: 160-162℃
    2. Boiling Point: 572.161 °C at 760 mmHg
    3. Flash Point: 299.832 °C
    4. Appearance: /
    5. Density: 1.20
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 16.70±0.46(Predicted)
    10. CAS DataBase Reference: Arterolane(CAS DataBase Reference)
    11. NIST Chemistry Reference: Arterolane(664338-39-0)
    12. EPA Substance Registry System: Arterolane(664338-39-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 664338-39-0(Hazardous Substances Data)

664338-39-0 Usage

Uses

Used in Pharmaceutical Industry:
Arterolane is used as an antimalarial drug for the treatment of uncomplicated Plasmodium falciparum malaria. It is combined with piperaquine to enhance the effectiveness against drug-resistant strains of the parasite.
Used in Malaria Treatment:
Arterolane is used as a therapeutic agent for reducing parasitemia, which is crucial in managing the symptoms and preventing the progression of malaria. Its rapid action helps in controlling the infection and ensuring the patient's recovery.
Used in Drug Resistance Management:
Arterolane is used as a component in antimalarial drug combinations to combat the issue of drug resistance in Plasmodium falciparum malaria. Its inclusion in treatment regimens helps in maintaining the effectiveness of antimalarial drugs and reducing the likelihood of resistance development.

Check Digit Verification of cas no

The CAS Registry Mumber 664338-39-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,4,3,3 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 664338-39:
(8*6)+(7*6)+(6*4)+(5*3)+(4*3)+(3*8)+(2*3)+(1*9)=180
180 % 10 = 0
So 664338-39-0 is a valid CAS Registry Number.

664338-39-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Arterolane

1.2 Other means of identification

Product number -
Other names OZ277

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:664338-39-0 SDS

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664338-39-0Downstream Products

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