664357-35-1

Basic information

• Product Name: 4-{[2-bromo-4-(3,3,6,6-tetramethyl-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydro-9-acridinyl)phenoxy]methyl}benzoic acid
• Synonyms: 4-{[2-bromo-4-(3,3,6,6-tetramethyl-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydro-9-acridinyl)phenoxy]methyl}benzoic acid
• CAS NO: 664357-35-1
• Molecular Formula: C31H32BrNO5
• Molecular Weight: 578.49348
• Mol File: 664357-35-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-{[2-bromo-4-(3,3,6,6-tetramethyl-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydro-9-acridinyl)phenoxy]methyl}benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[2-bromo-4-(3,3,6,6-tetramethyl-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydro-9-acridinyl)phenoxy]methyl}benzoic acid(664357-35-1)
• EPA Substance Registry System: 4-{[2-bromo-4-(3,3,6,6-tetramethyl-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydro-9-acridinyl)phenoxy]methyl}benzoic acid(664357-35-1)

Safety Data

• Hazardous Substances Data: 664357-35-1(Hazardous Substances Data)

Upstream product

• 126-81-8 dimedone 
• 2973-78-6 3-bromo-4-hydroxybenzylaldehyde 
• 6232-88-8 4-bromomethylbenzoic Acid 

Relevant articles and documents

Application of acridinedione compound in preparation of anti-diabetic drug

The invention provides an application of an acridinedione compound in preparation of an anti-diabetic medicine, and belongs to the technical field of biological medicines. According to the invention,the results prove that the acridinedione compound can participate in a GPR40-PPAR gamma-PI3K/Akt-GLUT4 signal path by activating and up-regulating GPR40 protein expression so as to promote insulin secretion, increase glucose consumption of liver and muscle tissues and improve insulin resistance; the action target of the acridinedione compound is a GPR40 receptor, the insulin secretion promoting effect of the acridinedione compound has glucose dependence, and when the peripheral blood glucose is lower than a certain degree, the blood glucose reducing effect of the acridinedione compound disappears; and the acridinedione compound is prepared into the anti-diabetic medicine, and brand-new selection and strategy are provided for treatment of diabetes mellitus.