66455-27-4

Basic information

• Product Name: GLYCOPROTEIN, ALPHA1-ACID HUMAN
• Synonyms: AGP;ALPHA1-ACID GLYCOPROTEIN;ALPHA1-ACID GLYCOPROTEIN, HUMAN;ALPHA1-ACID GLYCOPROTEIN, HUMAN SERUM;ALPHA1-ACID GLYCOPROTEIN (OROSOMUCOID);ALPHA-1 ACID GLYCOPROTEIN PLASMA;ALPHA1-AG, HUMAN;ALPHA-1-SEROMUCOID, HUMAN
• CAS NO: 66455-27-4
• Molecular Formula: NULL
• Molecular Weight: 0
• Mol File: 66455-27-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• Solubility: H2O: 10 mg/mL, clear, colorless
• Merck: 13,8018
• CAS DataBase Reference: GLYCOPROTEIN, ALPHA1-ACID HUMAN(CAS DataBase Reference)
• NIST Chemistry Reference: GLYCOPROTEIN, ALPHA1-ACID HUMAN(66455-27-4)
• EPA Substance Registry System: GLYCOPROTEIN, ALPHA1-ACID HUMAN(66455-27-4)

Safety Data

• Hazard Codes: B
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 66455-27-4(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 66455-27-4 differently. You can refer to the following data:
1. GLYCOPROTEIN, ALPHA1-ACID HUMAN was used to study nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimine.
2. α1-Acid glycoprotein from human plasma has been used:as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayersto incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISAto study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors

General Description

α-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family.

Biochem/physiol Actions

α1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital.

Purification Methods

Purify the glycoprotein 1 acid by passage through a carboxymethyl cellulose column, then through a Sephadex G-25 column. [Aronson et al. J Biol Chem 243 4564 1968.]