66471-97-4

Upstream product

• 121389-51-3 5-hydroxymethyl-2,2-dimethyl-2'(H)-5',6'-dihydropyrano<3',4'-q>indanol 
• 121389-52-4 5-carboxyl-2,2-dimethyl-2'(H)-5',6'-dihydropyrano<3',4'-q>indan-1-one 
• 121389-53-5 5-bromomethylcyclopenta-6-one-7,7-dimethyl-3,4-dihydro-1(H)-2-benzopyran-1-one 
• 66471-99-6 cyclopenta-6-one-5,7,7-trimethyl-3,4-dihydro-1(H)-2-benzopyranone 

Relevant academic research and scientific papers

RHODIUM CATALYSED CYCLOADDITIONS - AN EFFICIENT REGIOSPECIFIC ROUTE TO CALOMELANOLACTONE

A short regiospecific synthesis of calomelanolactone has been devised in which the key step is a cycloaddition.

Divergent total syntheses of five illudalane sesquiterpenes and assignment of the absolute configuration

Concise, divergent total syntheses of five bioactive illudalane sesquiterpenes have been achieved. Our synthesis features an intermolecular [2+2+2] cycloaddition, and a lactone-directed aromatic C-H oxygenation to generate a temporary phenolic hydroxyl group which enables regioselective methylation. Furthermore, the absolute configuration of radulactone was assigned by chemical synthesis.

RHODIUM CATALYSED SYNTHESIS OF ILLUDALANES

A short, regiospecific route to pterosin Z and calomelanolactone is presented in which the key step is a rhodium catalysed intramolecular cycloaddition.