66472-41-1Relevant academic research and scientific papers
Chiral phosphoric acid catalyzed enantioselective [4 + 2] cycloaddition reaction of α-fluorostyrenes with imines
Terada, Masahiro,Kikuchi, Jun,Ye, Haiting
supporting information, p. 8957 - 8961 (2020/12/02)
An enantioselective [4 + 2] cycloaddition reaction of α-fluorostyrenes with N-benzoyl imines was demonstrated using a chiral phosphoric acid catalyst. Cycloaddition products having fluorine functionality were formed in high yields with excellent diastereo
Fluorination with ionic liquid EMIMF(HF)2.3 as mild HF source
Yoshino, Hideaki,Matsumoto, Kazuhiko,Hagiwara, Rika,Ito, Yasuhiko,Oshima, Koichiro,Matsubara, Seijiro
, p. 29 - 35 (2007/10/03)
Hydrogen fluoride is a basic fluorinating reagent, but handling it is difficult. For this reason, some modified fluorinating reagents such as HF-pyridine, Et3N-HF, and poly(hydrogen fluoride) complex have been developed. Those reagents, however, still require aqueous work-up procedures which generate hydrogen fluoride. Recently, ionic liquids have received much attention because of the ease in handling them and the possibility of non-aqueous work-up. An ionic liquid, 3-ethyl-1-methyimidazolium oligo hydrogen fluoride (EMIMF(HF)2.3), which is stable in air and moisture, can be used as a hydrogen fluoride equivalent for some fluorination reactions; it does not require an aqueous work-up.
A mild method for halofluorination of alkenes with ionic liquid EMIMF(HF)2.3
Yoshino, Hideaki,Matsubara, Seijiro,Oshima, Koichiro,Matsumoto, Kazuhiko,Hagiwara, Rika,Ito, Yasuhiko
, p. 121 - 123 (2007/10/03)
Halofluorination of alkene in the presence of N-halosuccinimide and ionic liquid, 3-ethyl-1-methyl-imidazorium oligo hydrogen fluoride (EMIMF(HF) 2.3), as a HF source was demonstrated. Various alkenes were converted into β-halo organofluorides
Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase
Rosen, Thomas C.,Yoshida, Shinichi,Fr?hlich, Roland,Kirk, Kenneth L.,Haufe, Günter
, p. 5860 - 5871 (2007/10/03)
A series of para-substituted diastereopure cis- and trans-2-fluoro-2- arylcyclopropylamines were synthesized and these were investigated as inhibitors of microbial tyramine oxidase from Arthrobacter sp. All compounds were shown to be competitive inhibitor
Halofluorination of alkenes with ionic liquid EMIMF(HF)2.3
Yoshino, Hideaki,Matsubara, Seijiro,Oshima, Koichiro,Matsumoto, Kazuhiko,Hagiwara, Rika,Ito, Yasuhiko
, p. 455 - 458 (2007/10/03)
Halofluorination of alkene by means of N-halosuccinimide and ionic liquid, 1-ethyl-3-methylimidazorium oligo hydrogenfluoride (EMIMF(HF)2.3), was demonstrated. Various alkenes were converted into β-halo organofluorides in good yields after non-
