6648-30-2Relevant academic research and scientific papers
Synthetic method of alpha-position dibromination of alpha-heterocyclic carbonyl compound
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Paragraph 0027-0028; 0063-0065, (2020/05/30)
The invention discloses a synthetic method of alpha-position dibromination of an alpha-heterocyclic carbonyl compound, and belongs to the technical field of organic synthesis, and the method comprisesthe following steps: by taking the alpha-heterocyclic carbonyl compound as a raw material, adding a bromination reagent, a solvent and a small molecular catalyst, and reacting under light irradiationto obtain a corresponding product. The method has the advantages of high yield, simplicity and convenience in operation, mild reaction conditions, wide substrate adaptability and the like.
Visible-light photoredox catalysis enabled bromination of phenols and alkenes
Zhao, Yating,Li, Zhe,Yang, Chao,Lin, Run,Xia, Wujiong
, p. 622 - 627 (2014/04/17)
A mild and efficient methodology for the bromination of phenols and alkenes has been developed utilizing visible light-induced photoredox catalysis. The bromine was generated in situ from the oxidation of Br- by Ru(bpy)33+, both of which resulted from the oxidative quenching process.
Trihaloisocyanuric acids as convenient reagents for regioselective halogenation of β-dicarbonyl compounds
Mendon?a, Gabriela F.,Sindra, Haryadylla C.,de Almeida, Leonardo S.,Esteves, Pierre M.,de Mattos, Marcio C.S.
scheme or table, p. 473 - 475 (2009/05/07)
The reaction of β-dicarbonyl compounds (β-ketoesters and β-diketones) with 0.34 mol equiv of trichloro- and tribromoisocyanuric acids produced regioselectively the corresponding α-monohalo β-dicarbonyl compound. On the other hand, utilization of 0.68 mol equiv of the trihaloisocyanuric acid produced the α,α-dihalo β-dicarbonyl compound.
