66495-86-1

Basic information

• Product Name: 2-(4-chlorophenyl)naphtho[2,1-b]furan
• Synonyms: 2-(4-chlorophenyl)naphtho[2,1-b]furan
• CAS NO: 66495-86-1
• Molecular Formula: C₁₈H₁₁ClO
• Molecular Weight: 278.73234
• Mol File: 66495-86-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-chlorophenyl)naphtho[2,1-b]furan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)naphtho[2,1-b]furan(66495-86-1)
• EPA Substance Registry System: 2-(4-chlorophenyl)naphtho[2,1-b]furan(66495-86-1)

Safety Data

• Hazardous Substances Data: 66495-86-1(Hazardous Substances Data)

Upstream product

• 1073-67-2 4-vinylbenzyl chloride 
• 135-19-3 β-naphthol 
• 873-73-4 4-n-chlorophenylacetylene 
• 573-97-7 1-bromo-2-naphthol 

Relevant articles and documents

BF3-catalyzed oxidative tandem annulation-aromatization of naphthols with terminal aryl alkenes

A metal-free oxidative arene/alkene annulation-aromatization has been realized, which enables efficient synthesis of 2-arylnaphtho[2,1-b]furans from readily available terminal aryl alkenes and 2-naphthols. Mechanistic study suggests that this reaction proceeds via free-radical initiated tandem cyclization, dehydrogenative rearomatization and aromatization.

Metal-Free Oxidative Annulation of 2-Naphthols with Terminal Alkynes Affording 2-Arylnaphtho[2,1-b]furans

For the first time, the selective oxidative transformation of 2-naphthols with terminal alkynes is disclosed, which enables the straightforward synthesis of 2-arylnaphtho[2,1-b]furans in satisfactory yields under metal-free conditions. Mechanistic study s

An efficient method to synthesize benzofurans and naphthofurans

A new method for synthesis of benzofurans and naphthofurans from 2-hydroxystilbene derivatives via an intermolecular cyclization is reported in this study with up to 94% isolated yield. Georg Thieme Verlag Stuttgart.