66496-82-0

Usage

Uses

Used in Pharmaceutical Industry:
3-CHLOROMETHYL-1-METHYLPIPERIDINE HYDROCHLORIDE is used as a precursor in the production of drugs. Its chloromethyl and methyl substituents allow for the synthesis of a wide range of pharmaceutical compounds, making it a valuable component in drug development.
Used in Organic Synthesis:
3-CHLOROMETHYL-1-METHYLPIPERIDINE HYDROCHLORIDE is used as a building block in the synthesis of various organic compounds. Its functional groups can be further modified or used as starting materials for the creation of new molecules, contributing to the advancement of organic chemistry.
Used in Research and Development:
3-CHLOROMETHYL-1-METHYLPIPERIDINE HYDROCHLORIDE is used as a research compound in the field of organic chemistry. Its unique structure and properties make it an interesting subject for study, potentially leading to new discoveries and applications in the pharmaceutical and chemical industries.

InChI:InChI=1/C7H14ClN.ClH/c1-9-4-2-3-7(5-8)6-9;/h7H,2-6H2,1H3;1H

Upstream product

• 7583-53-1 1-methyl-3-hydroxymethylpiperidine 

Downstream Products

• 942133-90-6 1-[2-hydroxy-3-methyl-4-[(1-methyl-3-piperidinyl)methoxy]phenyl]ethanone 
• 147847-97-0 2-(2,4-dichlorophenyl)-3-(1-methylpiperidin-3-yl)propionitrile 
• 417723-95-6 4-(4-amino-3-fluorophenoxy)-7-(1-methylpiperidin-3-ylmethoxy) quinoline-6-carbonitrile 
• 417714-20-6 N-(4-(6-Cyano-7-((1-methylpiperidin-3-yl)methoxy)-4-quinolyl)oxy-2-fluorophenyl)-N'-(4-fluorophenyl)urea 
• 174347-05-8 1-Methyl-3-(4-nitro-phenoxymethyl)-piperidine 
• 3689-38-1 2-chloro-10-[(1-methylpiperidin-3-yl)methyl]-10H-phenothiazine 
• 1348503-37-6 N-(1-methylethyl)-2-[3-[3-(methyloxy)phenyl]-7-{[(1-methyl-3-piperidinyl)methyl]oxy}-1-oxopyrrolo[1,2-a]pyrazin-2(1H)-yl]acetamide 
• 1100094-58-3 3-(1H-benzimidazol-2-yl)-5-[3-methoxy-4-[(1-methylpiperidin-3-yl)methoxy]phenyl]pyrazin-2-amine 

Relevant academic research and scientific papers

3-(methyleneaminoxy)methylpiperidine derivatives as uptake inhibitors of biogenic amines in the brain synaptosomal fraction

A series of 3-(methyleneaminoxy)methylpiperidines (5a-h) and their corresponding N-methyl derivatives (6a-h) with a variety of substituents on the imino carbon were synthesized and tested for their potential antidepressant properties; their capacity to inhibit the re-uptake of biogenic amines (NA, 5-HT and DA) in rabbit brain synaptosomal fractions was also evaluated.The biological results obtained for the piperidine derivatives 5a-h and 6a-h and viloxazine 1, the reference drug, on the 3 re-uptake systems revealed that compounds 5 and 6 are generally able to inhibitbiogenic amine uptake.The IC50 values for 5 and 6 were often lower than that of viloxazine 1, in particular for the serotonin- and/or dopamine-uptake systems.A higher activity was found for compounds substituted with at least one phenyl ring on the imino carbon with respect to completely aliphatic systems, and for N-unsubstituted compounds with respect to N-methyl-substituted compounds. 3-(methyleneaminoxy)methylpiperidine derivative / NA uptake inhibitor / 5-HT uptake inhibitor / DA uptake inhibitor / antidepressant drug