664972-15-0Relevant articles and documents
Identification of small molecule sphingomyelin synthase inhibitors
Deng, Xiaodong,Lin, Fu,Zhang, Ya,Li, Yan,Zhou, Lu,Lou, Bin,Li, Yue,Dong, Jibin,Ding, Tingbo,Jiang, Xiancheng,Wang, Renxiao,Ye, Deyong
, p. 1 - 7 (2014/01/17)
Sphingomyelin synthase (SMS), which catalyzes ceramide as one of the substrates to produce sphingomyelin, is a critical factor in the sphingolipid biosynthesis pathway. Recent studies indicated that SMS could serve as a novel potential drug target for the