664985-29-9Relevant academic research and scientific papers
Facile stereoselective synthesis of (E)-1-arylseleno-substituted 1,3-enynes and their applications in synthesis of (E)-enediynes
Fang, Xiaoniu,Jiang, Minhua,Hu, Ronghua,Cai, Mingzhong
experimental part, p. 4170 - 4181 (2009/04/11)
(E)-1-Iodo-2-arylselenoethylenes 1 underwent the Sonogashira coupling reactions with terminal alkynes 2 to afford (E)-1-arylseleno-substituted 1,3-enynes 3 in high yields. (E)-1-Arylseleno-substituted 1,3-enynes 3 were coupled with alkynylmagnesium bromides 4 in the presence of a catalytic amount of NiCl2(PPh3)2 to give stereoselectively (E)-enediynes 5 in good yields. Copyright Taylor & Francis Group, LLC.
