664998-04-3

Basic information

• Product Name: Uridine, 3-[(4-methoxyphenyl)methyl]-2',3'-O-(1-methylethylidene)-, 5'-(4-methylbenzenesulfonate)
• CAS NO: 664998-04-3
• Molecular Formula: C27H30N2O9S
• Molecular Weight: 558.609
• Mol File: 664998-04-3.mol

Chemical Properties

• CAS DataBase Reference: Uridine, 3-[(4-methoxyphenyl)methyl]-2',3'-O-(1-methylethylidene)-, 5'-(4-methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: Uridine, 3-[(4-methoxyphenyl)methyl]-2',3'-O-(1-methylethylidene)-, 5'-(4-methylbenzenesulfonate)(664998-04-3)
• EPA Substance Registry System: Uridine, 3-[(4-methoxyphenyl)methyl]-2',3'-O-(1-methylethylidene)-, 5'-(4-methylbenzenesulfonate)(664998-04-3)

Safety Data

• Hazardous Substances Data: 664998-04-3(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 32464-93-0 1-(2,3-O-Isopropylidene-β-D-ribofuranosyl)-3-(4-methoxybenzyl)uracil 

Downstream Products

• 664998-09-8 3-(4-methoxybenzyl)-1-[p-methoxybenzyl (11R)-2-azido-2,7-dideoxy-3,4:9,10-di-O-isopropylidene-6-keto-L-ribo-β-D-galacto-undecodialdo-1,5-pyranoside-11,8-furanosyl]uracil 
• 664998-07-6 1-(5-(N-nitroso)-acetamido-5-deoxy-2,3-O-isopropylidene-β-D-ribofuranosyl)-3-(4-methoxybenzyl)uracil 
• 664998-06-5 1-(5-acetamido-5-deoxy-2,3-O-isopropylidene-β-D-ribofuranosyl)-3-(4-methoxybenzyl)uracil 
• 664998-05-4 1-(5-azido-5-deoxy-2,3-O-isopropylidene-β-D-ribofuranosyl)-3-(4-methoxybenzyl)uracil 

Relevant articles and documents

Synthetic studies towards the tunicamycins and analogues based on diazo chemistry. Total synthesis of tunicaminyl uracil.

A synthetic approach to the tunicamycins, a complex family of nucleosides with potent antibiotic and antiviral activities is reported based on diazo chemistry. The corresponding precursors for the synthesis of tunicaminyl uracil derivatives, the non-stabilized diazo derived from 13 and the aldehyde derivative of uridine, compound 4, were prepared efficiently from commercially available D-galactal and uridine, respectively. After a high yielding coupling reaction to obtain the ketone 14, a stereoselective reduction provided the corresponding tunicaminyl uracil derivative 17a and its C-7 epimer 17b. The interconversion of the diazo and aldehyde functional groups in the requisite building blocks was similarly achieved to obtain the ketone 32, which after reduction yielded the corresponding 7-deoxy-6-hydroxy tunicaminyl uracil analogs 33a and 33b.