66571-24-2

Basic information

• Product Name: 2-ethyl-2,3-dihydro-4H-1,3-benzoxazin-4-one
• CAS NO: 66571-24-2
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.1998
• Mol File: 66571-24-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 391°C at 760 mmHg
• Flash Point: 190.2°C
• Density: 1.125g/cm³
• Vapor Pressure: 2.55E-06mmHg at 25°C
• Refractive Index: 1.524
• CAS DataBase Reference: 2-ethyl-2,3-dihydro-4H-1,3-benzoxazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethyl-2,3-dihydro-4H-1,3-benzoxazin-4-one(66571-24-2)
• EPA Substance Registry System: 2-ethyl-2,3-dihydro-4H-1,3-benzoxazin-4-one(66571-24-2)

Safety Data

• Hazardous Substances Data: 66571-24-2(Hazardous Substances Data)

Upstream product

• 66570-99-8 2-ethynyl-2,3-dihydro-benzo[e][1,3]oxazin-4-one 
• 21725-69-9 3-hydroxybenzisoxazole 
• 123-38-6 propionaldehyde 
• 65-45-2 salicylamide 

Downstream Products

• 872988-84-6 4-[2-(2-ethyl-4-oxo-3,4-dihydro-2H-benzo[1,3]oxazin-3-yl)ethoxy]benzaldehyde 

Relevant articles and documents

Dual PPAR-α and -γ activators derived from novel benzoxazinone containing thiazolidinediones having antidiabetic and hypolipidemic potential

2,4-Thiazolidinedione derivatives of 1,3-benzoxazinone were synthesized and evaluated for their PPAR-α and -γ dual activation. DRF-2519, a compound obtained through SAR of TZD derivatives of benzoxazinone, has shown potent dual PPAR activation. In ob/ob mice, it showed better efficacy than the comparator molecules. In fat fed rat model, it showed significant improvement in lipid parameters, which was better than fibrates.