66605-77-4

Upstream product

• 13019-22-2 9-Decen-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 117560-76-6 methyl 4-(dec-9-enyloxy)benzoate 
• 142580-79-8 ethyl 4-(n-dec-9-en-1-yloxy)benzoate 
• 53179-04-7 undec-10-enenitrile 
• 165320-47-8 (-)-5-(9-decenyloxy)-2-[4-(6-ethoxy-1-heptyl)phenyl]pyrimidine 
• 165320-50-3 (-)-5-(9-decenyloxy)-2-[4-(6-propanoyloxy-1-heptyl)phenyl]-pyrimidine 
• 100566-35-6 2-Phenyl-3-(9-decenyloxy)-7-ethoxycarbonylmethylthio-pyrazolo[4,3-d]pyrimidine 
• 1009641-18-2 1,3,5-tris[3-(4-dec-9-enyloxyphenyl)isoxazol-5-yl]benzene 
• 1437766-21-6 N-(tert-butoxycarbonyl)bis[4-[(dec-9-en-1-yloxy)methyl]benzyl]amine 
• 5129-57-7 methyl 11-methyldodecanoate 

Relevant academic research and scientific papers

Novel phenolic antioxidant-functionalized dendritic polyethylene: Synthesis by tailor-made nickel(II) α-diimine-catalyzed copolymerization and its characteristics as non-releasing additive

This work describes a simple one-pot and controlled synthetic method to generate migration-resistant bio-friendly tailor-made antioxidants through ethylene–sterically hindered phenolic antioxidant (SHPA) copolymerization by coordination polymerization usi

Novel design and approach to latent fingerprint detection on paper using a 1,2-indanedione-based bi-functional reagent

A novel 1,2-indanedione-based bi-functional reagent was designed for the development of latent fingerprints on paper substrates. The reagent was synthesized using a concise five-step protocol and applied using a modified multi-metal deposition (MMD) proce

Fluorinated Analogues of the Histone Deacetylase Inhibitor Vorinostat (Zolinza): Validation of a Chiral Hybrid Bioisostere, BITE

A chiral, hybrid bioisostere of the CF3 and Et groups (BITE) was installed in a series of vorinostat (Zolinza) analogues, and their histone deacetylase (HDAC) inhibitory behavior was studied relative to that of their nonfluorinated counterparts. Several of these compounds containing the 1,2-difluoroethylene unit showed in vitro potency greater than that of the clinically approved drug itself against HDAC1. This trend was found to be general with the BITE-modified HDAC inhibitors performing significantly better than the ethyl derivatives. Installed by the direct, catalytic vicinal difluorination of terminal alkenes using an I(I)/I(III) manifold, this underexplored chiral bioisostere shows potential in drug discovery.

Metal-Free Activation of C-I Bonds and Perfluoroalkylation of Alkenes with Visible Light Using Phosphine Catalysts

An efficient metal-free, photomediated iodo perfluoroalkylation under mild conditions was developed. Using catalytic amounts (10 mol %) of phosphines and blue light irradiation, various olefins are transformed into the corresponding addition products with

PRODUCTION OF AMINES VIA A HYDROAMINOALKYLATION REACTION

Provided is a process for producing an amine via a hydroaminoalkylation reaction of a non-aromatic C-C double bond or C-C triple bond, said process comprising a step of reacting a compound comprising a non-aromatic C-C double bond or C-C triple bond with a reactive component which is obtainable by combining an aminal or a hemiaminal ether with an acidic medium comprising trifluoroacetic acid, wherein the aminal contains two amino groups independently selected from a secondary and a tertiary amino group that are linked by a methylene group wherein one hydrogen atom may be replaced by a further substituent, and at least one of the amino groups carries a hydrogen atom at a carbon atom bound in α-position to its nitrogen atom, and the hemiaminal ether contains a secondary or a tertiary amino group which carries a hydrogen atom at a carbon atom bound in α-position to its nitrogen atom, and the secondary or tertiary amino group is linked to an alkoxy group by a methylene group wherein one hydrogen atom may be replaced by a further substituent.

Branch-Selective Addition of Unactivated Olefins into Imines and Aldehydes

Radical hydrofunctionalization occurs with ease using metal-hydride hydrogen atom transfer (MHAT) catalysis to couple alkenes and competent radicalophilic electrophiles. Traditional two-electron electrophiles have remained unreactive. Herein we report the reductive coupling of electronically unbiased olefins with imines and aldehydes. Iron catalysis allows addition of alkyl-substituted olefins into imines through the intermediacy of free radicals, whereas a combination of catalytic Co(Salt-Bu,t-Bu) and chromium salts enables a branch-selective coupling of olefins and aldehydes through the formation of a putative alkyl chromium intermediate.

Long-Chain Alkyl Cyanides: Unprecedented Volatile Compounds Released by Pseudomonas and Micromonospora Bacteria

The analysis of volatiles from bacterial cultures revealed long-chain aliphatic nitriles, a new class of natural products. Such nitriles are produced by both Gram-positive Micromonospora echinospora and Gram-negative Pseudomonas veronii bacteria, although the structures differ. A variable sequence of chain elongation and dehydration in the fatty acid biosynthesis leads to either unbranched saturated or unsaturated nitriles with an ω?7 double bond, such as (Z)-11-octadecenenitrile, or methyl-branched unsaturated nitriles with the double bond located at C-3, such as (Z)-13-methyltetradec-3-enenitrile. The nitrile biosynthesis starts from fatty acids, which are converted into their amides and finally dehydrated. The structures and biosyntheses of the 19 naturally occurring compounds were elucidated by mass spectrometry, synthesis, and feeding experiments with deuterium-labeled precursors. Some of the nitriles showed antimicrobial activity, for example, against multiresistant Staphylococcus aureus strains.

Aerobic Acetoxyhydroxylation of Alkenes Co-catalyzed by Organic Nitrite and Palladium

An aerobic acetoxyhydroxylation of alkenes cooperatively catalyzed by organic nitrite and palladium at room temperature using clean and cheap air as the sole oxidant has been developed. Various vicinal diols, diacetoxyalkanes, and dihalogenoalkanes have been synthesized. The gram-scale synthesis has also been approached. Vicinal difluorination and dichlorolation products have also been achieved via this reaction.

Fine-tuning latent fingerprint detection on paper using 1,2-indanedione bi-functional reagents

In order to address the need for consistency and generality in chemical methods developed for detection of latent fingerprints on paper substrates, a practical protocol was developed using 1,2-indanedione-based bi-functional reagents. A series of novel bi

Effects of alkyl side chain modification of coenzyme Q10 on mitochondrial respiratory chain function and cytoprotection

The effect of the alkyl side chain length of coenzyme Q10 on mitochondrial respiratory chain function has been investigated by the use of synthetic ubiquinone derivatives. Three analogues (3, 4 and 6) were identified that exhibited significantl