66607-48-5

Basic information

• Product Name: 2-(benzylamino)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
• Synonyms: 2-(benzylamino)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one
• CAS NO: 66607-48-5
• Molecular Weight: 285.37
• Mol File: 66607-48-5.mol

Chemical Properties

• CAS DataBase Reference: 2-(benzylamino)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzylamino)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one(66607-48-5)
• EPA Substance Registry System: 2-(benzylamino)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one(66607-48-5)

Safety Data

• Hazardous Substances Data: 66607-48-5(Hazardous Substances Data)

Upstream product

• 332163-80-1 ethyl 4,5-dimethyl-2-(1H-tetrazol-1-yl)thiophene-3-carboxylate 
• 100-46-9 benzylamine 

Relevant articles and documents

New Convenient Strategy for Annulation of Pyrimidines to Thiophenes or Furans via the One-pot Multistep Cascade Reaction of 1 H -Tetrazoles with Aliphatic Amines

A versatile, convenient, efficient and high-yield synthetic method for 2-R3,R4-amino-5-R1-6-R2-thieno[2,3-d]pyrimidin-4(3H)-ones, 2-R3,R4-amino-5-R1-6-R2-thieno[3,2-d]pyrimidin-4(3H)-ones, and benzofuro[3,2-d]pyrimidin-4(3H)-ones preparation has been developed. The reaction proceeded without using solvents and included several steps. A variety of thieno[2,3-d]pyrimidine and thieno[3,2-d]pyrimidine derivatives with substituents of different nature were obtained in high yields from substituted alkyl 2-(1H-tetrazol-1-yl)thiophene-3-carboxylates, 3-(1H-tetrazol-1-yl)thiophene-2-carboxylates, and 3-(1H-tetrazol-1-yl)benzofuran-2-carboxylate after their treatment with aliphatic amines.