66612-09-7

Basic information

• Product Name: 2-(dimethylamino)-1-methylpyridinium iodide
• CAS NO: 66612-09-7
• Molecular Formula: C₈H₁₃IN₂
• Molecular Weight: 264.1067
• Mol File: 66612-09-7.mol

Chemical Properties

• CAS DataBase Reference: 2-(dimethylamino)-1-methylpyridinium iodide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(dimethylamino)-1-methylpyridinium iodide(66612-09-7)
• EPA Substance Registry System: 2-(dimethylamino)-1-methylpyridinium iodide(66612-09-7)

Safety Data

• Hazardous Substances Data: 66612-09-7(Hazardous Substances Data)

Usage

Appearance

Yellow to brown colored solid

Solubility

Soluble in polar solvents such as water and methanol

Use in organic synthesis

Reactant in the preparation of various pyridinium salts and other organic compounds

Catalytic properties

Commonly used as a catalyst in chemical reactions, particularly those involving carbon-carbon bond formations

Antimicrobial properties

Exhibits antimicrobial and antifungal properties

Applications

Useful in the field of pharmaceuticals and biotechnology

Upstream product

• 5683-33-0 2-(Dimethylamino)pyridine 
• 627-31-6 1,3-Diiodopropane 
• 74-88-4 methyl iodide 

Relevant articles and documents

Amidine dications as superelectrophiles

2-Dimethylalkylammonium pyridinium and 2-dimethylalkylammonium pyrimidinium ditriflate salts are very powerful methylating agents toward phosphorus (triphenylphosphine) and nitrogen (triethylamine) nucleophiles. In competition experiments with triethylamine as nucleophile, these N-methyl disalts are more reactive methylating agents than dimethyl sulfate. Reaction of the pyridinium dications with water as an oxygen nucleophile leads to attack at the 2-position of the heteroaromatic ring and displacement of an ammonium group; 2-hydroxypyridinium compounds are formed in the first instance, which are easily converted to 2-pyridones. Extending the scope of the reactions, a tricationic 2,6-bis(dimethylalkylammonium) pyridinium salt has also been prepared and characterized and its reactivity as a methylating agent assessed in comparison with that of the dications.