666175-03-7

Basic information

• Product Name: Benzenecarboximidoyl chloride, 3-chloro-N-(3-chlorophenyl)-
• CAS NO: 666175-03-7
• Molecular Formula: C13H8Cl3N
• Molecular Weight: 284.572
• Mol File: 666175-03-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenecarboximidoyl chloride, 3-chloro-N-(3-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarboximidoyl chloride, 3-chloro-N-(3-chlorophenyl)-(666175-03-7)
• EPA Substance Registry System: Benzenecarboximidoyl chloride, 3-chloro-N-(3-chlorophenyl)-(666175-03-7)

Safety Data

• Hazardous Substances Data: 666175-03-7(Hazardous Substances Data)

Upstream product

• 618-46-2 m-Chlorobenzoyl chloride 
• 10286-92-7 3-Chloro-N-(3-chlorophenyl)benzamide 

Downstream Products

• 350486-68-9 3-chloro-N-(3-chlorophenyl)-N'-hydroxybenzimidamide 

Relevant articles and documents

New insights into the bacterial RNA polymerase inhibitor CBR703 as a starting point for optimization as an anti-infective agent

CBR703 was reported to inhibit bacterial RNA polymerase (RNAP) and biofilm formation, considering it to be a good candidate for further optimization. While synthesized derivatives of CBR703 did not result in more-active RNAP inhibitors, we observed promising antibacterial activities. These again correlated with a significant cytotoxicity toward mammalian cells. Furthermore, we suspect the promising effects on biofilm formation to be artifacts. Consequently, this class of compounds can be considered unattractive as antibacterial agents. Copyright