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666227-05-0

2-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-erythro-pentofuranosyl]-6-{[(dimethylamino)methylidene]amino}-2H-pyrazolo[3,4-d]pyrimidin-4-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 666227-05-0 Structure

  • Basic information

    1. Product Name: 2-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-erythro-pentofuranosyl]-6-{[(dimethylamino)methylidene]amino}-2H-pyrazolo[3,4-d]pyrimidin-4-one
    2. Synonyms: 2-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-erythro-pentofuranosyl]-6-{[(dimethylamino)methylidene]amino}-2H-pyrazolo[3,4-d]pyrimidin-4-one
    3. CAS NO:666227-05-0
    4. Molecular Formula:
    5. Molecular Weight: 624.696
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 666227-05-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-erythro-pentofuranosyl]-6-{[(dimethylamino)methylidene]amino}-2H-pyrazolo[3,4-d]pyrimidin-4-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-erythro-pentofuranosyl]-6-{[(dimethylamino)methylidene]amino}-2H-pyrazolo[3,4-d]pyrimidin-4-one(666227-05-0)
    11. EPA Substance Registry System: 2-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-erythro-pentofuranosyl]-6-{[(dimethylamino)methylidene]amino}-2H-pyrazolo[3,4-d]pyrimidin-4-one(666227-05-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 666227-05-0(Hazardous Substances Data)

666227-05-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 666227-05-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,6,2,2 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 666227-05:
(8*6)+(7*6)+(6*6)+(5*2)+(4*2)+(3*7)+(2*0)+(1*5)=170
170 % 10 = 0
So 666227-05-0 is a valid CAS Registry Number.

666227-05-0Downstream Products

666227-05-0Relevant articles and documents

Oligonucleotide duplexes containing N8-glycosylated 8-aza-7-deazaguanine and self-assembly of 8-aza-7-deazapurines on the nucleoside and the oligomeric level.

Seela, Frank,Kroeschel, Rita

, p. 3900 - 3908 (2003)

The 8-aza-7-deazaguanine N8-(2'-deoxy-beta-D-ribofuranoside) (1) was synthesized, converted into the phosphoramidite 4 and incorporated into oligonucleotides. Nucleoside 1 forms stable base pairs with 2'-deoxy-5-methylisocytidine in DNA with antiparallel chain orientation (aps) and with 2'-deoxycytidine in duplexes with parallel chains (ps). According to the CD spectra self-complementary oligonucleotides d(1-m5isoC)3 and d(1-C), form autonomous DNA-structures. Neither the nucleoside 1 nor the regularly linked 8-aza-7-deaza-2'-deoxyguanosine form G-like tetrads while the regularly linked 8-aza-7-deaza-2'-deoxyisoguanosine gives higher molecular assemblies which are destroyed by bulky 7-bromo substituents. This was verified on monomeric nucleosides by ESI-MS spectrometry and on oligonucleotides by HPLC analysis.

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