666235-09-2Relevant academic research and scientific papers
Nickel-catalyzed oxidative coupling reactions of two different terminal alkynes using O2 as the oxidant at room temperature: Facile syntheses of unsymmetric 1,3-diynes
Yin, Weiyan,He, Chuan,Chen, Mao,Zhang, Heng,Lei, Aiwen
supporting information; scheme or table, p. 709 - 712 (2009/08/12)
(Formula Presented) Two different terminal alkynes now can be coupled together in the presence of NiCl2-6H2O/Cul by using an excess of one of the terminal alkyne substrates. The new method employed 20 mol % TMEDA as the ligand and environmentally benign O2 or air as the oxidant. It is the first example using Ni-salt as catalyst by employing air or O2 as oxidant, which led to efficient heterocoupling of two different alkynes.
Reactivity and selectivity of 1,3-diyn-6-enes in electrophilic transition metal-catalyzed reactions
Cho, Eun Jin,Kim, Mansuk,Lee, Daesung
, p. 5413 - 5416 (2007/10/03)
1,3-Diyne is an excellent source of alkynyl metal carbene species upon activation with an electrophilic metal catalyst. The products from this bond reorganization process suggest that the metal carbene species, generated from the preferential participatio
