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(E)-1-methyl-2-(phenylimino)indolin-3-one is a chemical compound with the molecular formula C16H13N2O. It is an indolinone derivative, characterized by a 3-one functional group, a phenylimino group, and a methyl group at the 1-position. (E)-1-methyl-2-(phenylimino)indolin-3-one is known for its potential applications in the synthesis of various pharmaceuticals and organic compounds due to its unique structure and reactivity. It is an important intermediate in the preparation of certain biologically active molecules and can be used in the development of new drugs and chemical entities. The compound's properties, such as its stability and reactivity, make it a valuable component in organic synthesis and medicinal chemistry research.

66625-56-7

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66625-56-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 66625-56-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,6,2 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 66625-56:
(7*6)+(6*6)+(5*6)+(4*2)+(3*5)+(2*5)+(1*6)=147
147 % 10 = 7
So 66625-56-7 is a valid CAS Registry Number.

66625-56-7Relevant academic research and scientific papers

Syntheses of 2-Iminoindolin-3-ones and 2-Alknyl-2,3-dihydroquinazolin-4(1 H)-ones from 3-Diazoindolin-2-imines

Lin, Zhenwei,Qian, Jing,Lu, Ping,Wang, Yanguang

, p. 11766 - 11777 (2020/10/23)

3-Diazoindolin-2-imines reacted with nitrones to furnish 2-iminoindolin-3-ones through a Au(I)-catalyzed cascade oxygen transfer/imine exchange process. The prepared 2-iminoindolin-3-ones could be further transformed into 2-Alknyl-2,3-dihydroquinazolin-4(1H)-ones through a Ag(I)-catalyzed reaction with terminal alkynes. A MeOH-Triggered ring expansion mechanism involving cyclic iminium formation and nucleophilic addition is proposed for this novel alkynylation reaction. This two-step procedure provides a general and convenient approach to 2-Alknyl-2,3-dihydroquinazolin-4(1H)-ones, which are privileged structures in medicinal chemistry.

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