666256-77-5Relevant academic research and scientific papers
Control of product distribution in the domino metathesis reactions of N-alkynyl 2-azabicyclo[2.2.1]hept-5-en-3-ones. A convenient synthesis of functionalized γ-lactams and indolizidinones
Arjona, Odón,Csák?, Aurelio G.,León, Vanessa,Medel, Rocío,Plumet, Joaquín
, p. 565 - 567 (2004)
In this report we describe the domino metathesis of N-alkynyl-2-aza-3-oxo- [2.2.1]hept-5-enes. The distribution of products of the domino processes of ROM-CM or ROM-RCM-CM depends on the starting material and on the catalyst used. A sequence of metathesis events has been proposed to account for these results. The procedure can be of use for the synthesis of lactams and indolizidinones.
