66632-18-6

Upstream product

• 532-80-9 synephrine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 942421-62-7 4-{2-[(tert-butoxycarbonyl)(methyl)amino]-1-hydroxyethyl}phenyl hexanoate 
• 942421-61-6 4-{2-[(tert-butoxycarbonyl)(methyl)amino]-1-hydroxyethyl}phenyl isobutyrate 
• 942421-63-8 4-{2-[(tert-butoxycarbonyl)(methyl)amino]-1-hydroxyethyl}phenyl 1-naphthoate 

Relevant academic research and scientific papers

A new and efficient route for the synthesis of naturally occurring catecholamines

Catecholamines, sympathomimetic drugs and adrenergic receptor antagonists, have been prepared by a regioselective oxidation of the corresponding 4-hydroxyphenethylamine derivatives by 2-iodoxybenzoic acid (IBX) in homogeneous as well as in heterogeneous conditions and followed by cleavage of the amino protective group. By using polymer-supported IBX, after the first oxidation, the oxidant can be recovered, regenerated, and efficiently reused for several additional times. An efficient, easy and green procedure for the synthesis of N-(methoxycarbonyl)dopamine, key component of many pharmaceuticals, has also been reported. Georg Thieme Verlag Stuttgart.

SYNEPHRINE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS

This invention provides compounds having the structural formula: wherein:- R1 is an acyl or sulfonyl group, - R2 is an acyl group selected from the group consisting of acyl groups derived from cycloaliphatic, aromatic or heterocyclic