66647-66-3Relevant academic research and scientific papers
Tripodal N,P Mixed-Donor Ligands and Their Cobalt Complexes: Efficient Catalysts for Acceptorless Dehydrogenation of Secondary Alcohols
Xu, Shi,Alhthlol, Latifah M.,Paudel, Keshav,Reinheimer, Eric,Tyer, David L.,Taylor, Daniela K.,Smith, Amberlynn M.,Holzmann, Jonathan,Lozano, Edgar,Ding, Keying
supporting information, p. 2394 - 2397 (2018/03/09)
A new tetradentate tripodal ligand, iPrPPPNHPyMe, and the cobalt complexes were synthesized and characterized. The well-defined cobalt complexes efficiently catalyzed acceptorless dehydrogenation of secondary alcohols into ketones.
Ruthenium-catalyzed self-coupling of primary and secondary alcohols with the liberation of dihydrogen
Makarov, Ilya S.,Madsen, Robert
, p. 6593 - 6598 (2013/07/26)
The dehydrogenative self-condensation of primary and secondary alcohols has been studied in the presence of RuCl2(IiPr)(p-cymene). The conversion of primary alcohols into esters has been further optimized by using magnesium nitride as an additive, which allows the reaction to take place at a temperature and catalyst loading lower than those described previously. Secondary alcohols were dimerized into racemic ketones by a dehydrogenative Guerbet reaction with potassium hydroxide as the additive. The transformation gave good yields of the ketone dimers with a range of alkan-2-ols, whereas more substituted secondary alcohols were unreactive. The reaction proceeds by dehydrogenation to the ketone, followed by an aldol reaction and hydrogenation of the resulting enone.
