66651-44-3

Upstream product

• 128729-18-0 N-Methylsulfinyl-3,5-di-t-butylaniline 
• 2380-36-1 3,5-di-tert-butylaniline 
• 3144-09-0 methanesulfonamide 
• 22385-77-9 1-bromo-3,5-di-tert-butylbenzene 

Downstream Products

• 114763-90-5 N-(2,4-Di-tert-butyl-6-methanesulfonylamino-phenyl)-N-(3,5-di-tert-butyl-phenyl)-methanesulfonamide 
• 80167-08-4 N,N'-bis(3,5-di-tert-butylphenyl)-N,N'-bis(methylsulfonyl)hydrazine 

Relevant academic research and scientific papers

Mild Pd-catalyzed N -arylation of methanesulfonamide and related nucleophiles: Avoiding potentially genotoxic reagents and byproducts

A convenient, general, and high yielding Pd-catalyzed cross-coupling of methanesulfonamide with aryl bromides and chlorides is reported. The use of this method eliminates concern over genotoxic impurities that can arise when an aniline is reacted with methanesulfonyl chloride. The application of this method to the synthesis of dofetilide is also reported.

Electron Spin Resonance Spectra of Sulfinamidyl Radicals and a Comparison of Hyperfine Splitting Constants with Sulfenamidyl and Sulfonamidyl Radicals

An ESR spectroscopic study of N-arylsulfinyl- and N-alkylsulfinyl-3,5-di-t-butylphenylaminyls (2) is described.The sulfinamidyls 2, generated by the reaction of the corresponding sulfinamides (7) with di-t-butyl diperoxyoxalate (DBPO) in benzene at 21 or