66660-80-8Relevant articles and documents
Novel oxime ethers
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, (2008/06/13)
The invention relates to novel oxime ethers of the formula I STR1 wherein R stands for a phenyl group which may be substituted by a halogen atom or by one or more C1 -C4 alkoxy, hydroxyl, nitro or di(C1 -C3 alkyl)amino groups, R1 and R2 denote each a hydrogen atom or together a valence bond, A denotes a C2 -C4 straight or branched-chain alkylene group, N denotes an integer from 3 to 10, and R3 and R4 denote a hydrogen atom or a C1 -C4 alkyl group, furthermore to acid addition salts and quaternary ammonium salts thereof. These new compounds are biologically active, and possess primarily local analgesic, spasmolytic, nicotine-lethality inhibiting, tetrabenazine-antagonistic and tetra-cor-spasm inhibiting effects.