666726-72-3 Usage
Uses
Used in Pharmaceutical Research:
1(2H)-Quinolinecarboxylic acid, 4-[1-[(2E)-2-butenyloxy]ethyl]-6-(2-methoxyphenyl)-2,2-dimethyl-, 1,1-dimethylethyl ester is used as a key compound in pharmaceutical research for the development of new drugs and treatments. Its unique structure and functional groups make it a promising candidate for various therapeutic applications.
Used in Drug Development:
In the drug development industry, 1(2H)-Quinolinecarboxylic acid, 4-[1-[(2E)-2-butenyloxy]ethyl]-6-(2-methoxyphenyl)-2,2-dimethyl-, 1,1-dimethylethyl ester is utilized as a starting material or intermediate for the synthesis of novel therapeutic agents. Its potential therapeutic properties and unique structural features contribute to the design and development of innovative drugs targeting various medical conditions.
Used in Medicinal Chemistry:
1(2H)-Quinolinecarboxylic acid, 4-[1-[(2E)-2-butenyloxy]ethyl]-6-(2-methoxyphenyl)-2,2-dimethyl-, 1,1-dimethylethyl ester is employed in medicinal chemistry as a valuable building block for the creation of new chemical entities. Its structural diversity and functional group versatility allow for the exploration of various chemical modifications, leading to the discovery of potential therapeutic agents with improved efficacy and selectivity.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1(2H)-Quinolinecarboxylic acid, 4-[1-[(2E)-2-butenyloxy]ethyl]-6-(2-methoxyphenyl)-2,2-dimethyl-, 1,1-dimethylethyl ester serves as an important intermediate for the preparation of a wide range of complex organic molecules. Its unique structural features and functional groups enable the synthesis of diverse chemical compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 666726-72-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,6,7,2 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 666726-72:
(8*6)+(7*6)+(6*6)+(5*7)+(4*2)+(3*6)+(2*7)+(1*2)=203
203 % 10 = 3
So 666726-72-3 is a valid CAS Registry Number.
666726-72-3Relevant academic research and scientific papers
Discovery and SAR study of novel dihydroquinoline-containing glucocorticoid receptor agonists
Takahashi, Hidenori,Bekkali, Younes,Capolino, Alison J.,Gilmore, Thomas,Goldrick, Susan E.,Kaplita, Paul V.,Liu, Lisa,Nelson, Richard M.,Terenzio, Donna,Wang, Ji,Zuvela-Jelaska, Ljiljana,Proudfoot, John,Nabozny, Gerald,Thomson, David
, p. 5091 - 5095 (2008/02/12)
We have recently reported the discovery of a novel class of glucocorticoid receptor (GR) antagonists, exemplified by 3, containing a 1,2-dihydroquinoline molecular scaffold. Further SAR studies of these antagonists uncovered chemical modifications conveying agonist functional activity to this series. These agonists exhibit good GR binding affinity and are selective against other nuclear hormone receptors.
GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
-
Page 72-73, (2010/02/06)
Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, X, Y, and n are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
