666727-29-3Relevant academic research and scientific papers
Discovery and SAR study of novel dihydroquinoline containing glucocorticoid receptor ligands
Takahashi, Hidenori,Bekkali, Younes,Capolino, Alison J.,Gilmore, Thomas,Goldrick, Susan E.,Nelson, Richard M.,Terenzio, Donna,Wang, Ji,Zuvela-Jelaska, Ljiljana,Proudfoot, John,Nabozny, Gerald,Thomson, David
, p. 1549 - 1552 (2007/10/03)
We report the discovery of a novel class of glucocorticoid receptor (GR) ligands based on 1,2-dihydroquinoline molecular scaffold. The compounds exhibit good GR binding affinity and selectivity profile against other nuclear hormone receptors.
