66674-90-6Relevant academic research and scientific papers
A simple one-pot synthesis of 2,6-disubstituted 4-(polyfluoroalkyl) pyridines and -pyrimidines by reaction of 2-polyfluoroalkylchromones with aromatic methyl ketimines and amidines
Sosnovskikh, Vyacheslav Ya.,Usachev, Boris I.,Sizov, Aleksei Yu.,Barabanov, Mikhail A.
, p. 942 - 948 (2004)
The reaction of 2-polyfluoroalkylchromones with ketimines, derived from aromatic methyl ketones and isopropylamine, gives 2,6-diaryl-4- polyfluoroalkylpyridines in moderate to low yields. Benzamidine and guanidine also react with 2-polyfluoroalkylchromones to afford the corresponding 2,6-disubstituted 4-polyfluoroalkylpyrimidines.
