666746-27-6

Basic information

• Product Name: TERT-BUTYL 4-IODO-2-METHYLPHENYLCARBAMATE
• Synonyms: TERT-BUTYL 4-IODO-2-METHYLPHENYLCARBAMATE;N-Boc-4-iodo-2-Methylaniline
• CAS NO: 666746-27-6
• Molecular Formula: C₁₂H₁₆INO₂
• Molecular Weight: 333.16541
• Mol File: 666746-27-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 310.6 °C at 760 mmHg
• Flash Point: 141.7 °C
• Appearance: /
• Density: 1.536 g/cm³
• Storage Temp.: 2-8°C(protect from light)
• Water Solubility: at 25 deg C (mg/L): 0.5886
• CAS DataBase Reference: TERT-BUTYL 4-IODO-2-METHYLPHENYLCARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 4-IODO-2-METHYLPHENYLCARBAMATE(666746-27-6)
• EPA Substance Registry System: TERT-BUTYL 4-IODO-2-METHYLPHENYLCARBAMATE(666746-27-6)

Safety Data

• Hazardous Substances Data: 666746-27-6(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-iodo-2-methylphenylcarbamate, also known as iopamidol, is a chemical compound commonly used as a contrast medium in medical imaging procedures such as CT scans and angiography. It is a radiocontrast agent that increases the visibility of organs and tissues in the body during imaging, allowing for clearer and more detailed diagnostic images. Iopamidol is a nonionic contrast agent that is well tolerated by most patients and has a low risk of adverse side effects. It is typically administered intravenously and rapidly distributed throughout the body, providing enhanced visualization of blood vessels, organs, and other structures. Due to its efficient and effective imaging properties, iopamidol is widely used in clinical settings for diagnostic purposes.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 13194-68-8 4-iodo-2-methylaniline 

Downstream Products

• 666746-53-8 t-butyl 4-(3-oxo-1-butenyl)-2-methylcarbanilate 
• 666746-34-5 2-methyl-4-(1-trifluoromethylethenyl)aniline 
• 916975-25-2 tert-butyl [4-(3,5-bis-n-perfluorobutylbenzyl)-2-methylphenyl]-carbamate 
• 916975-26-3 4-(3,5-bis-n-perfluorobutylbenzyl)-2-methylaniline 
• 1263300-10-2 5-cyclopropyl-2-phenyl-1H-indole 
• 1263300-09-9 tert-butyl [4-cyclopropyl-2-(2-oxo-2-phenylethyl)phenyl]carbamate 
• 1263300-08-8 tert-butyl (4-cyclopropyl-2-methylphenyl)carbamate 
• 849370-56-5 t-butyl 4-[1-(4-chlorophenyl)-2,2,2-trifluoro-1-hydroxyethyl]-2-methylcarbanilate 
• 849370-46-3 t-butyl 4-[1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoro-1-hydroxyethyl]-2-methylcarbanilate 
• 849370-54-3 t-butyl 4-[3-(4-chlorophenyl)-1-hydroxy-1-trifluoromethyl-2-propenyl]-2-methylcarbanilate 
• 849370-49-6 t-butyl 4-[2,2,2-trifluoro-1-hydroxy-1-(4-trifluoromethoxyphenyl)-ethyl]-2-methylcarbanilate 
• 849370-44-1 t-butyl 4-[1-hydroxy-1-(5-trifluoromethylpyridin-2-yl)ethyl]-2-methylcarbanilate 
• 666746-28-7 t-butyl 2-methyl-4-(1-trifluoromethylethenyl)carbanilate 
• 666746-46-9 tertiary butyl 4-[1-(4-chlorophenyl)-1-hydroxyethyl]-2-methylcarbanilate 

Relevant articles and documents

MITOCHONDRIAL COMPLEX I INHIBITORS AND METHODS OF USE

Disclosed herein are methods of using mitochondrial complex I inhibitors in the treatment of a disease or condition that would benefit from the inhibition of mitochondrial respiration. Also described herein are methods of treating a disease or condition s