666752-28-9

Basic information

• Product Name: 1,1'-DiBOC-3,3'-diindolylmethane
• Synonyms: 1,1'-DiBOC-3,3'-diindolylmethane
• CAS NO: 666752-28-9
• Molecular Formula: C27H30N2O4
• Molecular Weight: 446.54
• Mol File: 666752-28-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,1'-DiBOC-3,3'-diindolylmethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-DiBOC-3,3'-diindolylmethane(666752-28-9)
• EPA Substance Registry System: 1,1'-DiBOC-3,3'-diindolylmethane(666752-28-9)

Safety Data

• Hazardous Substances Data: 666752-28-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1968-05-4 3,3'-diindolylmethane 
• 700-06-1 indole-3-carbinol 
• 249762-98-9 bis(1H-2-indolyl)methane 

Relevant articles and documents

ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION

Compounds useful as antibacterial agents are provided. The compounds are analogs of indole-3-carbinol and have a backbone selected from dihydroindolo[2,3-b]carbazole, 2,2'-diindolylmethane, 2',3-diindolylmethane, and 3,3'-diindolylmethane. The compounds are useful therapeutic and prophylactic treatment of bacterial infections in mammals. Methods of synthesis of the compounds are provided, as are pharmaceutical compositions containing the compounds.

Analogs of indole-3-carbinol metabolites as chemotherapeutic and chemopreventive agents

Novel compounds useful as chemotherapeutic and chemopreventive agents are provided. The compounds are analogs of indole-3-carbinol metabolites wherein the structures and substituents of the compounds are selected to enhance the compounds' overall efficacy, particularly with respect to therapeutic activity, oral bioavailability, long-term safety, patient tolerability, and therapeutic window. The compounds are useful not only in treatment of cancer but also in prevention of cancer. One preferred class of the novel compounds have the structure of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are defined herein. Pharmaceutical compositions are provided as well, as are methods of synthesis and use.