666824-79-9Relevant academic research and scientific papers
Stereoselective carbon-carbon bond forming reactions between various chiral alkyl aryl carbinols and triethyl methanetricarboxylate by oxidation-reduction condensation using alkyl diphenylphosphinites
Mukaiyama, Teruaki,Nagata, Yuzo,Ikegai, Kazuhiro
, p. 1676 - 1677 (2005)
Oxidation-reduction condensation reactions between alkyl diphenylphosphinites derived from chiral alkyl aryl carbinols and triethyl methanetricarboxylate proceeded smoothly to afford the corresponding condensation products in good yields with inversion of stereochemistries. Copyright
FLAVIN DERIVATIVES
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Page/Page column 194-195, (2011/10/31)
The present invention relates novel flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives.
Stereoselective Carbon-Carbon Bond Formation via the Mitsunobu Displacement of Chiral Secondary Benzylic Alcohols
Hillier, Michael C.,Desrosiers, Jean-Nicolas,Marcoux, Jean-Francois,Grabowski, Edward J. J.
, p. 573 - 576 (2007/10/03)
(Matrix presented) The stereoselective displacement of a variety of chiral benzylic alcohols with triethylmethanetricarboxylate (TEMT) under Mitsunobu conditions (DEAD, PMe3) has been demonstrated to proceed in good yield (70-94%) and with a high degree of inversion. Subsequent saponification and decarboxylation of the products thus obtained provide chiral 3-aryl-3-substituted propanoic acids without racemization.
