666845-13-2

Upstream product

• 439096-21-6 [[1-(4-AMINO-PHENYL)-PIPERIDIN-4-YL]-ACETIC] acid ethyl ester 
• 256397-61-2 6-methyl-4'-trifluoromethyl-1,1'-biphenyl-2-carboxylic acid 
• 256397-64-5 [6-METHYL-4'-(TRIFLUOROMETHYL)-[1, 1'-BIPHENYL]-2-CARBONYL] 

Downstream Products

• 666845-23-4 the maleate addition salt of compound ⁽¹⁰⁾ 
• 666845-22-3 the methanesulfonate addition salt of compound ⁽¹⁰⁾ 
• 666845-21-2 the hydrochloric acid addition salt of compound ⁽¹⁰⁾ 

Relevant academic research and scientific papers

N-ARYL PIPERIDINE SUBSTITUTED BIPHENYLCARBOXAMIDES

N-aryl piperidine substituted biphenylcarboxamides compounds of formula (I), methods for preparing compounds, pharmaceutical compositions comprising said compounds as wee as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.

N-ARYL PIPERIDINE SUBSTITUTED BIPHENYLCARBOXAMIDES AS INHIBITORS OF APOLIPOPROTEIN B SECRETION

N-aryl piperidine substituted biphenylcarboxamides compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes. The compounds act as inhibitors of apolipoprotein B.