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2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-hydroxyacetamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

66695-69-0

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66695-69-0 Usage

Derivative of isoindoline

The compound is based on the isoindoline structure, which is a fused bicyclic ring system.

Contains a hydroxyacetamide functional group

The presence of this functional group gives the compound specific chemical properties and reactivity.

Potential pharmaceutical applications

The compound has potential as a drug due to its structural similarity to bioactive molecules.

Histone deacetylase inhibitor

The compound exhibits biological activity by inhibiting the enzyme histone deacetylase, which is involved in the regulation of gene expression.

Potential treatment for cancer and neurodegenerative diseases

The inhibition of histone deacetylase has been linked to the treatment of these types of diseases.

Subject of interest in research and drug development

The unique structure and biological activity of the compound make it a valuable target for further study and potential development into new drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 66695-69-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,6,9 and 5 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 66695-69:
(7*6)+(6*6)+(5*6)+(4*9)+(3*5)+(2*6)+(1*9)=180
180 % 10 = 0
So 66695-69-0 is a valid CAS Registry Number.

66695-69-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(1,3-dioxoisoindol-2-yl)-N-hydroxyacetamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66695-69-0 SDS

66695-69-0Relevant academic research and scientific papers

An Environmentally Sustainable Mechanochemical Route to Hydroxamic Acid Derivatives

Mocci, Rita,De Luca, Lidia,Delogu, Francesco,Porcheddu, Andrea

supporting information, p. 3135 - 3144 (2016/10/09)

An operationally simple, and cost efficient conversion of carboxylic acids into hydroxamic acid derivatives via a high-energy mechanochemical activation is presented. This ball milling methodology was applied to a wide variety of carboxylic acids dramatically improving purification issues associated with this class of molecules, which still remain one of the main bottlenecks of classical methodologies. (Figure presented.).

Amino acid-based reoxidants for aminohydroxylation: Application to the construction of amino acid-amino alcohol conjugates

Donohoe, Timothy J.,Callens, Cedric K. A.,Flores, Aida,Mesch, Stefanie,Poole, Darren L.,Roslan, Ishmael A.

, p. 10957 - 10960 (2012/01/05)

A viable nitrogen source for the aminohydroxylation reaction of terminal alkenes: By adding a N-O based reoxidant onto an amino acid acyl carbon atom, compounds were obtained that facilitated catalytic turnover and also promoted the conjugation of an amino acid with an alkene. High levels of regioselectivity were observed, as well as good stereoselectivity induced by catalytic amounts of a chiral ligand.

Phthaloyl amino acid hydroxamic acids

-

, (2008/06/13)

A series of phthaloyl amino acid hydroxamic acids are useful as inhibitors of Angiotensin I converting enzyme.

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