6672-30-6

Basic information

• Product Name: (R)-(+)-3-METHYLCYCLOPENTANONE
• Synonyms: (R)-(+)-3-METHYLCYCLOPENTANONE;Cyclopentanone, 3-methyl-, (R)-;(3R)-3-Methylcyclopentanone;(R)-(+)-3-Methylcyclopentanone 99%;(3R)-3-methylcyclopentan-1-one
• CAS NO: 6672-30-6
• Molecular Formula: C₆H₁₀O
• Molecular Weight: 98.14
• EINECS: 229-711-6
• Product Categories: Chiral Building Blocks;Ketones;Organic Building Blocks
• Mol File: 6672-30-6.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 143-144 °C(lit.)
• Flash Point: 98 °F
• Appearance: /
• Density: 0.914 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.434(lit.)
• CAS DataBase Reference: (R)-(+)-3-METHYLCYCLOPENTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-3-METHYLCYCLOPENTANONE(6672-30-6)
• EPA Substance Registry System: (R)-(+)-3-METHYLCYCLOPENTANONE(6672-30-6)

Safety Data

• Statements: 10
• Safety Statements: 16-29-33
• RIDADR: UN 1224 3/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 6672-30-6(Hazardous Substances Data)

Usage

General Description

"(R)-(+)-3-Methylcyclopentanone" is a chiral organic compound that is used in various chemical reactions and synthesis processes. It is a cyclic ketone with a methyl group attached to the third carbon atom in the cyclopentanone ring. (R)-(+)-3-METHYLCYCLOPENTANONE is commonly used as a building block in the production of pharmaceuticals, flavoring agents, and perfumes. It can also be utilized as a solvent in some industrial processes. The (R)-(+)-3-Methylcyclopentanone has potential applications in the fields of medicine, food, and fragrance industries due to its unique chemical properties.

InChI:InChI=1S/C6H10O/c1-5-2-3-6(7)4-5/h5H,2-4H2,1H3/t5-/m0/s1

Upstream product

• 3973-43-1 4-methylpent-4-enal 
• 118621-18-4 (2R,4R)-2-Methoxy-4-methyl-cyclopentanone 
• 930-30-3 cyclopent-2-enone 
• 544-97-8 dimethyl zinc(II) 
• 30213-19-5 cis-3,5-bis(hydroxymethylene)cyclopent-4-ene 
• 1757-42-2 3-methyl-cyclopentanone 
• 2758-18-1 3-Methyl-2-cyclopenten-1-one 
• 118621-16-2 (R)-(+)-5-methoxycyclopent-2-en-1-one 
• 111057-57-9 (3S,3aS,4R,7S,7aR)-3-Methyl-2,3,3a,4,7,7a-hexahydro-4,7-methano-inden-1-one 
• 129569-55-7 (3aS,4S,7R,7aS)-1-Oxo-1,4,7,7a-tetrahydro-4,7-methano-indene-3a-carboxylic acid ethyl ester 
• 105500-35-4 (1R,2S,6R,7S)-tricyclo[5.2.1.0(2,6)]deca-4,8-dien-3-one 
• 82136-15-0 6-(Toluene-4-sulfinyl)-1,4-dioxa-spiro[4.4]non-6-ene 
• 88269-13-0 (+)-(1S,5R)-3-oxabicyclo<3.2.1>octan-2-one 
• 108160-69-6 ethyl (1S,3R)-3-methylprclopentanecarboxylate 

Downstream Products

• 114218-64-3 (R)-1-methyl-cyclopentan-3-one-phenylhydrazone 
• 61898-55-3 (4R)-4-methyltetrahydro-2H-pyran-2-one 
• 2857-75-2 (R)-4-methyl-δ-valerolactone 
• 342652-10-2 (Z)-cyano-((R)-3-methyl-cyclopentylidene)-acetic acid ethyl ester 
• 342652-12-4 (E)-cyano-((R)-3-methyl-cyclopentylidene)-acetic acid ethyl ester 
• 61898-56-4 (S)-4-methyltetrahydro-2H-pyran-2-one 
• 1394045-13-6 (S)-2-(methoxymethoxy)-2-((1R,2R,3R)-3-methyl-2-vinylcyclopentyl)propan-1-ol 
• 1394045-11-4 (R,E)-7-hydroxy-2,6-dimethylhept-5-enyl 4-methylbenzenesulfonate 
• 1394045-10-3 (R,E)-ethyl 2,6-dimethyl-7-(tosyloxy)hept-2-enoate 
• 1120-62-3 3-methyl-1-cyclopentene 
• 96-37-7 methyl-cyclopentane 
• 5078-75-1 1-Phenyl-3-methylcyclopentylbenzen 
• 152518-80-4 (1R,2R)-1-phenyl-2-methylcyclopentane 
• 152518-79-1 (1R,2R)-1-phenyl-2-methylcyclopentane 

Relevant articles and documents

Synthesis of optically pure 3R-methylcyclopentan-1-one from L-(-)-menthol

Synthesis of optically pure 3R-methylcyclopentan-1-one using in the key step Dieckmann cyclization of diisopropyl 3R-methylhexan-1,6-dioate, which is accessible from L-(-)-menthol, was proposed. 2005 Springer Science+Business Media, Inc.

Counterion Enhanced Organocatalysis: A Novel Approach for the Asymmetric Transfer Hydrogenation of Enones

We present a novel strategy for organocatalytic transfer hydrogenations relying on an ion-paired catalyst of natural l-amino acids as main source of chirality in combination with racemic, atropisomeric phosphoric acids as counteranion. The combination of a chiral cation with a structurally flexible anion resulted in a novel chiral framework for asymmetric transfer hydrogenations with enhanced selectivity through synergistic effects. The optimized catalytic system, in combination with a Hantzsch ester as hydrogen source for biomimetic transfer hydrogenation, enabled high enantioselectivity and excellent yields for a series of α,β-unsaturated cyclohexenones under mild conditions. Moreover, owing to the use of readily available and chiral pool-derived building blocks, it could be prepared in a straightforward and significantly cheaper way compared to the current state of the art.

Enantio- A nd regioselective: Ene-reductions using F420H2-dependent enzymes

In the past decade it has become clear that many microbes harbor enzymes that employ an unusual flavin cofactor, the F420 deazaflavin cofactor. Herein we show that F420-dependent reductases (FDRs) can successfully perform enantio-, regio- A nd chemoselective ene-reductions. For the first time, we have demonstrated that F420H2-driven reductases can be used as biocatalysts for the reduction of α,β-unsaturated ketones and aldehydes with good conversions (>99%) and excellent regioselectivities and enantiomeric excesses (>99% ee). Noteworthily, FDRs typically display an opposite enantioselectivity when compared to the well established FMN-dependent Old Yellow Enzymes (OYEs).