66741-06-8

Basic information

• Product Name: N'-cyclopentylidenebenzenesulfonohydrazide
• Synonyms: N'-cyclopentylidenebenzenesulfonohydrazide
• CAS NO: 66741-06-8
• Molecular Weight: 238.31
• Mol File: 66741-06-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N'-cyclopentylidenebenzenesulfonohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-cyclopentylidenebenzenesulfonohydrazide(66741-06-8)
• EPA Substance Registry System: N'-cyclopentylidenebenzenesulfonohydrazide(66741-06-8)

Safety Data

• Hazardous Substances Data: 66741-06-8(Hazardous Substances Data)

Upstream product

• 120-92-3 cyclopentanone 
• 80-17-1 benzenesufonyl hydrazide 

Downstream Products

• 14633-46-6 (cyclopentylsulfonyl)benzene 
• 21573-70-6 (cyclopent-1-en-1-yl)(phenyl)methanone 
• 125846-18-6 1-(dimethyl(phenyl)silyl)cyclopentan-1-ol 
• 146759-05-9 cyclopent-1-en-1-yldimethyl(phenyl)silane 

Relevant articles and documents

Direct Access to α,β-Unsaturated Ketones via Rh/MgCl2-Mediated Acylation of Vinylsilanes

We report herein the facile and practical construction of α,β-unsaturated ketones via rhodium-catalyzed direct acylation of vinylsilanes with readily available and abundant carboxylic acids. This protocol features access to a diverse array of synthetically useful functionalities with moderate to excellent yields. More importantly, the late-stage functionalization of pharmaceuticals was also realized with synthetically useful yield.

Silanes in Organic Synthesis. 8. Preparation of Vinylsilanes from Ketones and Their Regiospecific Cyclopentenone Annulation

A general method is described for the formation of vinylsilanes from ketones.Thus, conversion to the benzene- or p-toluenesulfonylhydrazone and sequential treatment with n-butyllithium and chlorotrimethylsilane in anhydrous tetramethylethylenediamine proceeds regiospecifically to afford the less substituted vinylsilane (in unsymmetrical cases).Friedel-Crafts acylation with acryloyl chlorides and aluminium chloride and subsequent Nazarov cyclization with Lewis acid catalysis results in cyclopentenone annulation.Numerous examples that reveal the scope of this processare described.Due to accompanying polymerization, annulation with acryloyl chloride itself is least efficient.This complication can, however, be averted through use of β-chloropropionyl chloride and dehydrochlorination with 1,5-diazabicycloundec-5-ene prior to ring closure.