667440-80-4 Usage
General Description
2-(2,3-Dimethyl-phenoxy)-2-methyl-propionic acid, also known as fenofibric acid, is a chemical compound used in the treatment of high cholesterol and triglyceride levels. It is a derivative of fibric acid and works by reducing the production of triglycerides and increasing the levels of "good" cholesterol in the blood. This, in turn, helps to lower the risk of heart disease and stroke. Fenofibric acid is often prescribed in combination with a healthy diet and lifestyle changes to maximize its effectiveness. It is available in various forms, including tablets and capsules, and is usually taken once a day with food. Side effects may include stomach upset, muscle pain, and liver problems, so it should only be used under the supervision of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 667440-80-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,7,4,4 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 667440-80:
(8*6)+(7*6)+(6*7)+(5*4)+(4*4)+(3*0)+(2*8)+(1*0)=184
184 % 10 = 4
So 667440-80-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H16O3/c1-8-6-5-7-10(9(8)2)15-12(3,4)11(13)14/h5-7H,1-4H3,(H,13,14)
667440-80-4Relevant articles and documents
Pd(II)-catalyzed ortho - Or meta-C-H olefination of phenol derivatives
Dai, Hui-Xiong,Li, Gang,Zhang, Xing-Guo,Stepan, Antonia F.,Yu, Jin-Quan
supporting information, p. 7567 - 7571 (2013/06/27)
A combination of weakly coordinating auxiliaries and ligand acceleration allows for the development of both ortho- and meta-selective C-H olefination of phenol derivatives. These reactions demonstrate the feasibility of directing C-H functionalizations when functional groups are distal to target C-H bonds. The meta-C-H functionalization of electron-rich phenol derivatives is unprecedented and orthogonal to previous electrophilic substitution of phenols in terms of regioselectivity. These methods are also applied to functionalize α-phenoxyacetic acids, a fibrate class of drug scaffolds.
CANNABINOID RECEPTOR MODULATOR
-
Page/Page column 54, (2008/06/13)
A cannabinoid receptor modulator containing a compound represented by Formula (I0) wherein, X is an oxygen atom, etc., R° is an optionally substituted acylamino group, ring A0 is a benzene ring which may further have a substituent in addition to R°, and ring B is an optionally substituted 5-membered heterocycle, or a salt thereof or a prodrug thereof.
