667453-67-0 Usage
Derivative of benzenediamine
1,3-Phenylenediamine
Explanation
1,3-Benzenediamine,4-ethyl-N1,N1-dimethyl-(9CI) is derived from benzenediamine, which is a compound containing two amine groups (-NH2) attached to a benzene ring.
Explanation
Aromatic amines are a class of organic compounds that contain an amine group (-NH2) attached to an aromatic ring, such as benzene.
Explanation
This chemical compound is used in various industries due to its versatile properties, including the production of dyes, pigments, and polymers. It is also used in the manufacturing of plastics, hair dyes, and pharmaceuticals.
Explanation
1,3-Benzenediamine,4-ethyl-N1,N1-dimethyl-(9CI) is classified as toxic, which means it can cause harm to living organisms, including humans.
Explanation
Exposure to this chemical can cause irritation to the skin and eyes, as well as respiratory problems if inhaled.
Explanation
When working with 1,3-Benzenediamine,4-ethyl-N1,N1-dimethyl-(9CI), it is essential to follow proper safety procedures and handling guidelines to minimize the risk of exposure and potential health hazards.
Classification
Aromatic amine
Applications
Dyes, pigments, polymers, plastics, hair dye, and pharmaceuticals
Toxicity
Considered toxic
Health hazards
Skin and eye irritation, respiratory issues
Safety precautions
Proper handling and safety measures required
Check Digit Verification of cas no
The CAS Registry Mumber 667453-67-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,7,4,5 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 667453-67:
(8*6)+(7*6)+(6*7)+(5*4)+(4*5)+(3*3)+(2*6)+(1*7)=200
200 % 10 = 0
So 667453-67-0 is a valid CAS Registry Number.
667453-67-0Relevant academic research and scientific papers
THIAZOLE DERIVATIVES USEFUL AS MUTANT IDH1 INHIBITORS FOR TREATING CANCER
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Paragraph 0116; 0120, (2018/04/12)
A compound of Formula II or a pharmaceutically acceptable salt thereof, wherein CyN is a cyclic amine group bound via a nitrogen atom; X is C or N; R1 and R2 are each independently a halogen, CN, CF3, CHF2, CH2F, a C1-C10alkyl group, a C1-C10alkoxy group, a di(C1-C5alkyl)amino; m and n are each independently 1, 2, or 3, and represents either a single bond or a double bond, wherein the racemic mixture of 3-(4-(4-chlorophenyl)thiazol-2-yl)-1-(2-ethyl-5-methoxyphenyl)-6-(2-methylprop-1-en-1-yl)-5-(piperazine-1-carbonyl)pyridin-2(1H)-one atropisomers is excluded.
MUTANT IDH1 INHIBITORS USEFUL FOR TREATING CANCER
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Paragraph 0218; 0223, (2016/07/27)
Compounds of Formula I and Formula II and the pharmaceutically acceptable salts thereof are disclosed The variables A, B, Y, Z, X1, X2, R1-4 and R13-18 are disclosed herein. The compounds are useful for treating cancer disorders, especially those involving mutant IDH1 enzymes. Pharmaceutical compositions containing compounds of Formula I or Formula II and methods of treatment comprising administering compounds of Formula I and Formula II are also disclosed.
