66751-91-5

Usage

Uses

Used in Pharmaceutical Industry:
(3E)-3-[2-(4-nitrophenyl)-2-oxoethylidene]-3,4-dihydroquinoxalin-2(1H)-one is used as a precursor in the synthesis of new drugs for its heterocyclic structure, which may contribute to the development of pharmaceuticals with novel biological activities.
Used in Agrochemical Industry:
(3E)-3-[2-(4-nitrophenyl)-2-oxoethylidene]-3,4-dihydroquinoxalin-2(1H)-one is used as a potential active ingredient in agrochemicals, particularly as a pesticide or herbicide, due to the presence of the nitro group which may confer these properties.
Further studies are necessary to fully explore and understand the potential uses and effects of (3E)-3-[2-(4-nitrophenyl)-2-oxoethylidene]-3,4-dihydroquinoxalin-2(1H)-one in both industries.

Upstream product

• 85635-72-9 p-nitrobenzoylpyruvanilide 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 403608-98-0 3-(4-nitrobenzoyl)pyrrolo[1,2-a]quinoxaline-1,2,4(5H)-trione 

Relevant academic research and scientific papers

Five-Membered 2,3-Dioxo Heterocycles. XXXIX. Reaction of 4-Aroyl-1-aryl-5-methoxycarbonyl- and 1-Aryl-4-isopropyloxalo-5-phenyl-2,3-dihydropyrrole-2,3-diones with o-Phenylenediamine

4-Aroyl-1-aryl-5-methoxycarbonyl- and 1-aryl-4-isopropyloxalo-5-phenyl-2,3-dihydropyrrole-2,3-diones react with p-phenylenediamine to give substituted 1,2,3,5,10,10a-hexahydropyrrolobenzodiazepine-2,3-diones.Hydrolysis of the latter yields 3-phenacylidene-1,2,3,4-tetrahydroquinoxalin-2-ones.

CHEMISTRY OF OXALYL DERIVATIVES OF METHYL KETONES. XXXV. KINETICS OF THE FORMATION OF 3-PHENACYLIDENE-3,4-DIHYDRO-2-QUINOXALONES FROM ARYLAMIDES OF AROYLPYRUVIC ACIDS AND o-PHENYLENEDIAMINE

The kinetics of the acid-catalyzed reactions of the arylamides of aroylpyruvic acids with o-phenylenediamine, leading to the formation of 3-phenacylidene-2-quinoxalones, were investigated.It was established that the reaction rate is controlled by nucleophilic attack by the amide carbonyl at the cyclization stage.