66759-18-0 Usage
Uses
Used in Cancer Treatment:
(5Z)-5-(1-methylpropylidene)imidazolidine-2,4-dione is used as an anti-cancer agent for the treatment of multiple myeloma and leprosy. It functions by modulating the immune system and inhibiting the growth of blood vessels, which helps in controlling tumor progression and reducing the severity of the disease.
Used in Autoimmune Disorders:
In the field of autoimmune disorders, (5Z)-5-(1-methylpropylidene)imidazolidine-2,4-dione is used as a therapeutic agent for conditions such as Beh?et's disease and Crohn's disease. Its immunomodulatory properties help in managing the symptoms and reducing the severity of these disorders.
Used in Pharmaceutical Industry:
(5Z)-5-(1-methylpropylidene)imidazolidine-2,4-dione is used as a research compound in the pharmaceutical industry for the development of new drugs and therapies. Its diverse range of biological activities and unique mechanism of action make it a valuable tool for understanding various disease processes and designing targeted treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 66759-18-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,7,5 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 66759-18:
(7*6)+(6*6)+(5*7)+(4*5)+(3*9)+(2*1)+(1*8)=170
170 % 10 = 0
So 66759-18-0 is a valid CAS Registry Number.
66759-18-0Relevant articles and documents
Synthesis and reactivity of 5-methylenehydantoins
Fraile, José M.,Lafuente, Gustavo,Mayoral, José A.,Pallarés, Antonio
experimental part, p. 8639 - 8647 (2011/11/30)
5-Methylenehydantoin, as well as the N-mono- and N,N-di-protected derivatives, can be obtained by different synthetic routes. These compounds can undergo a large variety of reactions, such as Diels-Alder, epoxidation, methanol addition and conjugate addition reactions of different types of nucleophiles, including carbon (cyanide), nitrogen (piperidine) and sulfur (thiols, thioacetate) nucleophiles. The reactivity with electrophilic reagents, such as m-CPBA or methanol in acidic medium, and the need for Lewis acids to promote the conjugate addition reactions indicate that hydantoin is a poor electron-withdrawing group.
