66760-19-8 Usage
Uses
Used in Pharmaceutical Industry:
4-(2-Hydroxyethyl)-1,2,4-triazole is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to impart biological activities to the final drug products. Its presence in the molecular structure can enhance the drug's efficacy, selectivity, and pharmacokinetic properties.
Used in Pesticide Industry:
In the pesticide industry, 4-(2-Hydroxyethyl)-1,2,4-triazole is utilized as a building block for the development of new pesticides. Its incorporation into pesticide molecules can improve their effectiveness against pests and diseases while potentially reducing environmental impact.
Used in Coordination Chemistry:
4-(2-Hydroxyethyl)-1,2,4-triazole is employed as a ligand in the field of coordination chemistry, where it forms metal ion coordination complexes. These complexes have potential applications in various areas, such as catalysis, sensing, and materials science, due to their unique properties and structures.
Used in Scientific Research:
4-(2-HYDROXYETHYL)-1,2,4-TRIAZOLE is also used in scientific research for studying its biological activities and exploring its potential applications in various fields. Researchers can use 4-(2-Hydroxyethyl)-1,2,4-triazole to develop new chemical entities, understand its interactions with biological targets, and investigate its role in different chemical and biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 66760-19-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,7,6 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 66760-19:
(7*6)+(6*6)+(5*7)+(4*6)+(3*0)+(2*1)+(1*9)=148
148 % 10 = 8
So 66760-19-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H7N3O/c8-2-1-7-3-5-6-4-7/h3-4,8H,1-2H2
66760-19-8Relevant academic research and scientific papers
ALKYLATION OF AZOLES USING beta -FUNCTIONAL ALKYL HALIDES UNDER CONDITIONS OF PHASE TRANSFER CATALYSIS.
Asratyan,Attaryan,Pogosyan,Eliazyan,Darbinyan,Matsoyan
, p. 1202 - 1206 (2007/10/02)
The objective of this study was to develop a convenient synthetic method for direct N-alkylation of pyrazole (I), 3(5)-methylpyrazole (II), 3,5-dimethylpyrazole (III), 1,2,4-triazole (IV), and tetrazole (V) using beta -functional alkyl halides under conditions of two-phase catalysis and with high product yields. This investigation was stimulated by the fact that the desired reaction products are intermediates in the synthesis of an important class of compounds, vinylazole, as well as of various pharmaceutical agents. It is found that depending on the acidity of the azole, alkylation with dichloroethane can be accompanied by beta -elimination. The effect of solvent on the course of alkylation reactions using dichloroethane has also been studied, and revealed that the reactions occur via the intermediacy of ion pairs rather than free anions.
