66782-11-4Relevant articles and documents
One-flow, multistep synthesis of nucleosides by Bronsted acid-catalyzed glycosylation
Sniady, Adam,Bedore, Matthew W.,Jamison, Timothy F.
supporting information; experimental part, p. 2155 - 2158 (2011/04/23)
Nucleosides in flow: A general, scalable method of Bronsted acid-catalyzed nucleoside formation is described. Because of the high reaction temperatures readily available to the flow reaction format, mild Bronsted acids, particularly pyridinium triflates, can be used. A one-flow multistep synthesis of unprotected nucleosides is also reported (see scheme).