667917-18-2

Basic information

• Product Name: (S)-2-(2-Hydroxy-3-{[(1S,3aR,6aS)-4-hydroxy-2-((S)-3-methyl-2-{(S)-3-methyl-2-[(pyrazine-2-carbonyl)-amino]-butyrylamino}-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carbonyl]-amino}-hexanoylamino)-3-phenyl-propionic acid tert-butyl ester
• CAS NO: 667917-18-2
• Molecular Weight: 807.988
• Mol File: 667917-18-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-(2-Hydroxy-3-{[(1S,3aR,6aS)-4-hydroxy-2-((S)-3-methyl-2-{(S)-3-methyl-2-[(pyrazine-2-carbonyl)-amino]-butyrylamino}-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carbonyl]-amino}-hexanoylamino)-3-phenyl-propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(2-Hydroxy-3-{[(1S,3aR,6aS)-4-hydroxy-2-((S)-3-methyl-2-{(S)-3-methyl-2-[(pyrazine-2-carbonyl)-amino]-butyrylamino}-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carbonyl]-amino}-hexanoylamino)-3-phenyl-propionic acid tert-butyl ester(667917-18-2)
• EPA Substance Registry System: (S)-2-(2-Hydroxy-3-{[(1S,3aR,6aS)-4-hydroxy-2-((S)-3-methyl-2-{(S)-3-methyl-2-[(pyrazine-2-carbonyl)-amino]-butyrylamino}-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carbonyl]-amino}-hexanoylamino)-3-phenyl-propionic acid tert-butyl ester(667917-18-2)

Safety Data

• Hazardous Substances Data: 667917-18-2(Hazardous Substances Data)

Upstream product

• 319011-86-4 (S)-3-Methyl-2-{(S)-3-methyl-2-[(pyrazine-2-carbonyl)-amino]-butyrylamino}-butyric acid 
• 402959-13-1 (S)-3-Methyl-2-{(S)-3-methyl-2-[(pyrazine-2-carbonyl)-amino]-butyrylamino}-butyric acid methyl ester 
• 402958-79-6 (1S,3aR,6aS)-4-Hydroxy-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid ethyl ester 
• 402958-22-9 (1S,3aR,6aS)-4-Hydroxy-hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-ethyl ester 
• 402958-21-8 (1S,3aR,6aS)-4-Oxo-hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-ethyl ester 
• 15100-75-1 L-phenylalanine tert-butyl ester hydrochloride 
• 69871-99-4 N-L-valyl-L-valine ; hydrochloride 
• 402958-29-6 2-(3-amino-2-hydroxy-hexanoylamino)-3-phenyl-propionic acid tert-butyl ester 
• 667468-10-2 (1S,3aR,6aS)-4-Hydroxy-2-((S)-3-methyl-2-{(S)-3-methyl-2-[(pyrazine-2-carbonyl)-amino]-butyrylamino}-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid 

Relevant articles and documents

Discovery of a novel bicycloproline P2 bearing peptidyl α-ketoamide LY514962 as HCV protease inhibitor

We describe herein the design, syntheses and evaluation of a number of bicycloproline P2 bearing HCV protease inhibitors endowed with impressive enzyme potency, enzyme selectivity, cellular activity and favorable ADME profiles.