668-40-6Relevant academic research and scientific papers
Total syntheses of daldiniapyrone, annularin B, and (±)-annularin F
Kurdyumov, Aleksey V.,Munoz, R. Lizeth P.,Hsung, Richard P.
, p. 1787 - 1790 (2006)
The first concise total syntheses of daldiniapyrone, annuarin B, and (±)-annularin F are described. Georg Thieme Verlag Stuttgart.
Studies on Metabolites of Macrophoma commelinae. IV. Substrate Specificity in the Biotransformation of 2-Pyrones to Substituted Benzoic Acids
Sakurai, Ikuo,Miyajima, Hisae,Akiyama, Katsuyoshi,Shimizu, Sakae,Yamamoto, Yuzuru
, p. 2003 - 2011 (2007/10/02)
Substrate specificity in the novel biotransformation from 2-pyrone derivatives to substituted benzoic acids by Macrophoma commelinae (IFO 9570) was investigated by means of feeding experiments with various compounds.Among them, 2-pyrone derivatives substituted by an electron-donating group at C-4, by an electron-withdrawing group at C-5 and by an alkyl group at C-6 were converted to the corresponding benzoic acid derivatives in fairly good yields.The C3-unit precursors and intermediates were examined in stationary or shaking culture.Based on the experimental results obtained, a mechanism for this unique reaction is proposed. macrophoma commelinae IFO 9570; fungi; 2-pyrone; substituted benzoic acid; biotransformation; substrate specificity; aromatic ring formation; macrophomic acid
