668273-75-4 Usage
Uses
Used in Pharmaceutical Industry:
Tert-butyl((3s)-1-(7-(but-2-yn-1-yl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,4,5,6,7-hexahydro-1h-purin-8-yl)piperidin-3-yl)carbaMate is used as an impurity in the synthesis of linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor. Linagliptin has potential use in the treatment of type 2 diabetes, making Tert-butyl((3s)-1-(7-(but-2-yn-1-yl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,4,5,6,7-hexahydro-1h-purin-8-yl)piperidin-3-yl)carbaMate an important component in the development and production of this medication.
Used in Research and Development:
Due to its unique structure and properties, Tert-butyl((3s)-1-(7-(but-2-yn-1-yl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,4,5,6,7-hexahydro-1h-purin-8-yl)piperidin-3-yl)carbaMate can be used in research and development for the discovery of new pharmaceutical compounds and therapeutic agents. Its interactions with various biological targets and its potential to modulate specific pathways make it a valuable tool in the advancement of medical science.
Used in Chemical Synthesis:
Tert-butyl((3s)-1-(7-(but-2-yn-1-yl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,4,5,6,7-hexahydro-1h-purin-8-yl)piperidin-3-yl)carbaMate can also be used in chemical synthesis processes, where its unique structure and reactivity can be exploited to create new molecules with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science. Its versatility and the ability to form stable intermediates make it a valuable building block in the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 668273-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,8,2,7 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 668273-75:
(8*6)+(7*6)+(6*8)+(5*2)+(4*7)+(3*3)+(2*7)+(1*5)=204
204 % 10 = 4
So 668273-75-4 is a valid CAS Registry Number.
668273-75-4Relevant academic research and scientific papers
METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN
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, (2015/12/20)
The present invention discloses an improved process for preparing an important intermediate of linagliptin. In particular, disclosed are a process for preparing a compound V which is an important intermediate of linagliptin and has the structure V, and an industrial process of preparing linagliptin having excellent chemical and optical purities, which is an inhibitor of dipeptidyl peptidase-4 (DPP-IV), from the compound V. The process employs a phase-transfer catalyst, is high in yield, easy and simple to handle, environmentally friendly, suitable for industrial mass production, and can be implemented by a “one-pot process”.
8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS MEDICAMENTS
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Page/Page column 73, (2008/06/13)
The invention relates to substituted xanthines of general formula (I) wherein R1 to R3 have the designations cited in patent claims 1 to 16, and to the tautomers, stereoisomers, mixtures, prodrugs and salts thereof, which have precio
