66831-17-2

Basic information

• Product Name: H-HYP(BZL)-OME HCL
• Synonyms: H-HYP(BZL)-OME HCL;HYDROXYPROLINE(BZL)-OME HCL;O-BENZYL-L-HYDROXYPROLINE METHYL ESTER HYDROCHLORIDE;O-BENZYL-L-4-HYDROXYPROLINE METHYL ESTER HYDROCHLORIDE;O-BENZYL-L-4-TRANS-HYDROXYPROLINE METHYL ESTER HYDROCHLORIDE;METHYL TRANS-4-BENZYLOXY-L-PROLINATE HYDROCHLORIDE ;(2S,4R)-4-Benzyloxy-pyrrolidine-2-carboxylic acid methyl ester hydrochloride;O-Benzoyl-L-Hydroxyproline methyl ester hydrochloride
• CAS NO: 66831-17-2
• Molecular Formula: C13H18ClNO3
• Molecular Weight: 271.74
• Mol File: 66831-17-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 331.6°C at 760 mmHg
• Flash Point: 154.3°C
• Appearance: /
• Vapor Pressure: 0.000154mmHg at 25°C
• Storage Temp.: -15°C
• CAS DataBase Reference: H-HYP(BZL)-OME HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-HYP(BZL)-OME HCL(66831-17-2)
• EPA Substance Registry System: H-HYP(BZL)-OME HCL(66831-17-2)

Safety Data

• Hazardous Substances Data: 66831-17-2(Hazardous Substances Data)

Usage

Chemical Properties

Off-white powder

Uses

H-Hyp(Bzl)-OMe HCl

InChI:InChI=1/C13H17NO3.ClH/c1-16-13(15)12-7-11(8-14-12)17-9-10-5-3-2-4-6-10;/h2-6,11-12,14H,7-9H2,1H3;1H/t11-,12+;/m1./s1

Upstream product

• 136024-60-7 1-(tert-butyl) 2-methyl (2S,4R)-4-(benzyloxy)pyrrolidine-1,2-dicarboxylate 
• 40216-83-9 L-4-hydroxyproline methyl ester hydrochloride 
• 74844-91-0 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate 

Downstream Products

• 1640024-27-6 C₂₂H₃₁N₃O₆ 
• 1620320-28-6 (7R,8aS)-3-allyl-7-(benzyloxy)hexahydropyrrolo[1,2-d][1,2,4]triazine-1,4-dione 
• 1620320-33-3 (7R)-7-(benzyloxy)-3-(but-3-en-1-yl)hexahydropyrrolo[1,2-d][1,2,4]triazine-1,4-dione 

Relevant articles and documents

Diastereoselective synthesis of novel aza-diketopiperazines via a domino cyclohydrocarbonylation/addition process

Herein, we report an unprecedented, short and diastereo-selective synthesis of newly reported aza-diketopiperazine (aza-DKP) scaffolds starting from amino acids. The strategy is based on a Rh(i)-catalyzed hydroformylative cyclohydrocarbonylation of allyl-substituted aza-DKP, followed by a diastereoselective functionalization of the platform. This methodology allows the synthesis of novel bicyclic and tricyclic aza-DKP scaffolds incorporating six- or seven-membered rings, with potential applications in medicinal chemistry. This journal is the Partner Organisations 2014.