66832-28-8

Basic information

• Product Name: 3-Pyrrolidinone, 1-(phenylmethyl)-, oxime
• CAS NO: 66832-28-8
• Molecular Formula: C11H14N2O
• Molecular Weight: 190.245
• Mol File: 66832-28-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyrrolidinone, 1-(phenylmethyl)-, oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyrrolidinone, 1-(phenylmethyl)-, oxime(66832-28-8)
• EPA Substance Registry System: 3-Pyrrolidinone, 1-(phenylmethyl)-, oxime(66832-28-8)

Safety Data

• Hazardous Substances Data: 66832-28-8(Hazardous Substances Data)

Downstream Products

• 18471-40-4 1-Benzyl-3-aminopyrrolidine 
• 61694-71-1 N-(1-benzyl-3-pyrrolidinyl)-4-amino-5-chloro-2-methoxybenzamide 
• 73328-60-6 N-(1-Benzyl-3-pyrrolidinyl)-5-chloro-2-methoxy-4-methylaminobenzamide 
• 61694-77-7 N-(1-benzyl-3-pyrrolidinyl)-5-chloro-4-dimethylamino-2-methoxybenzamide 
• 78784-41-5 N-(1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-formylamino-2-methoxy-benzamide 
• 78775-22-1 N-(1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-ethylamino-2-methoxy-benzamide 
• 78775-26-5 4-Acetylamino-N-(1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide 
• 78775-24-3 4-Benzylamino-N-(1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide 

Relevant articles and documents

Heterocyclization of oximes of 3,5-dimethyl(1,3,5-trimethyl)-2,6- diphenylpiperid-4-ones and N-benzylpyrrolid-3-ones with acetylene in a superbasic medium

It has been established that on heterocyclization of 3,5-dimethyl-2,6- diphenylpiperid-4-one oxime with acetylene in a superbasic medium migration of the 3a-CH3 group to the anionic nitrogen atom occurs, leading to the formation of 5,7-dimethyl-4,6-diphenyl-4,5,6,7-tetrahydropyrrolo[3,2-c]pyridine. The formation of the N-anion causes aromatization of the tetrahydropyridine ring. Tetrahydropyrrolo-[1,2-c]pyrimidines are formed in the Trofimov reaction as a result of decomposition of the intermediate 3H-pyrrole in a retro-Mannich reaction.