668475-28-3

Upstream product

• 103548-04-5 2-(tert-butyldimethylsilanyloxy)-1-phenylethan-1-one 
• 668475-12-5 4-(t-butyldimethylsilyloxy)-3-phenylbut-2-enoic acid ethyl ester 
• 668475-18-1 4-(t-butyldimethylsilyloxy)-3-phenylbut-2-en-1-ol 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 668475-23-8 (+/-)-3-(t-butyldimethylsilyloxymethyl)-3-phenylpent-4-enoic acid ethyl ester 

Downstream Products

• 668475-40-9 (+/-)-9-[3-(t-butyldimethylsilyloxymethyl)-3-phenylpent-4-enyl]adenine 
• 668475-34-1 (+/-)-1-O-methanesulfonic acid 3-(t-butyldimethylsilyloxymethyl)-3-phenylpent-4-enyl ester 

Relevant academic research and scientific papers

Novel synthesis of 4′C-aryl-branched acyclic nucleoside using [3,3]-sigmatropic rearrangement

A very efficient synthetic route for preparing a novel 4′-C-aryl branched-1′,2′-seco-2′,3′-dideoxy-2′, 3′-didehydro-nucleoside is described. Mesylate 7 was successfully synthesized via a Horner-Wadsworth-Emmons reaction and a [3,3]-sigmatropic rearrangeme